Results 91 to 100 of about 3,155,872 (310)

Origins of Relative Age Effects in Youth Football—A Nationwide Analysis

Frontiers in Sports and Active Living, 2020
Introduction: Relative age effects (RAEs) refer to the overrepresentation of players born earlier in the selection year compared to late-born players within the same age category. To date, the origins and mechanisms of RAEs are still unclear. To evaluate
Michael Romann, Eva Rüeger, Mirjam Hintermann, Raphael Kern, Oliver Faude   +4 more
doaj   +1 more source

Perspektif bimbingan dan konseling karir dalam era globalisasi [PDF]

, 2015
Career guidance is to prepare students to enter the selection process of interest and talent in the process of education, including college. On the other hand, career guidance also handles the process of choice and one's future career prospects to ...
Suryani, Ira
core   +1 more source

Personality attributes that predict cadet performance at West Point [PDF]

, 2017
Using data from the United States Military Academy at West Point (N = 1102 and N = 1049) from two successive years, we examined psychological measures of cadets and the correlations of those measures with consequential outcomes such as cadet performance ...
Mayer, John D., Skimmyhorn, William
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Relative age effects in German youth A and B men's soccer teams: survival of the fittest?

Frontiers in Sports and Active Living
The study investigates relative age effects (RAE) in German youth soccer (Youth Bundesliga A: January 2004 to December 2005 and B: January 2006 to December 2007; highest league in German youth soccer) and its persistence in third-division players.
Florian Heilmann, Alexander Kuhlig, Oliver Stoll   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Influence of Biological Maturation on the Career Trajectory of Football Players: Does It Predict Elite Success?

Journal of Functional Morphology and Kinesiology
Background: Early-maturing players tend to have physical advantages during formative stages, but it remains unclear whether these advantages translate into long-term professional success.
Saül Aixa-Requena, Albert Gil-Galve, Alejandro Legaz-Arrese, Vicenç Hernández-González, Joaquín Reverter-Masia   +4 more
doaj   +1 more source

Sectors Expansion, Allocation of Talent and Adverse Selection in Development [PDF]

This paper proposes a theory in which informational failures hindering an efficient operation of the economy are solved over the course development.
Esteban Jaimovich
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source