Results 41 to 50 of about 2,428,515 (232)

Exploring the Multidimensional Characteristics of Selected and Non-Selected White British and British South Asian Youth Cricketers: An Exploratory Machine Learning Approach

open access: yesYouth
Selection into a County Age Group (CAG; under 10–18) programme is the first step for young aspiring cricketers on their journey to achieving professional status.
Tom Brown   +5 more
doaj   +1 more source

Talent Selection and Management in View of Relative Age: the Case of Swimming

open access: yesPhysical Culture and Sport: Studies and Research, 2018
Based on our empirical research, through the analysis of the birthdates of young competitive swimmers, the present paper aims to examine the system of talent selection and management in Hungarian competitive swimming complemented with a new element.
Nagy Nikoletta   +3 more
doaj   +1 more source

An early start at a professional soccer academy is no prerequisite for world cup soccer participation

open access: yesFrontiers in Sports and Active Living, 2023
Introduction829 players from 32 nations on five continents participated in the 2022 men's World Cup tournament in Qatar. Not much is known about the youth careers of World Cup players from all over the world, especially about the age at which they began ...
Sebastiaan Willem-Jan Platvoet   +5 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Talent identification of 12-year old male Australian rules footballers: Physical advantages and prognosis for junior and senior national-level selection.

open access: yesPLoS ONE
Talent identification focuses on the ability to identify and select young athletes who show potential for future sporting success. The aim of this study was to compare the anthropometry and physical performance of male youth Australian Football players ...
Paul Larkin   +2 more
doaj   +1 more source

The relative age in handball players in Portugal

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2020
Relative age effect is a subject that has been studied as a differentiating factor between athletes’ development. This study aimed to determine whether handball players have more possibilities to get to high performance, according to the month and year ...
Paulo Sá   +4 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Storm Clouds on the Horizon: On the Emerging Need to Tighten Selection Policies

open access: yesFrontiers in Sports and Active Living, 2021
Athlete selection is fundamental in elite sport, occurring regularly throughout an athlete's development. Research in this area reveals the accuracy of these decisions is questionable in even the most elite sport environments and athletes are ...
Kathryn Johnston, Lou Farah, Joe Baker
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Talent Management - Case Study on Determining the Collective Pool of Talent [PDF]

open access: yesRisk in Contemporary Economy, 2012
Our paper focuses on the importance of attracting and retaining talent in a company. Attracting talent refers not only to the selection of talented employees from outside the company, but also to their identification among existing employees by ...
Mirabela-Constanta MATEI   +2 more
doaj  

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