Results 121 to 130 of about 419,034 (302)

Determining and Prioritizing Admission Criteria for Talented Students Office in Isfahan University of Medical Sciences Using Analytical Hierarchy Process Model [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2007
Introduction: Students' scores on university entrance exam (Conquer) or their average scores are not appropriate criteria to recognize them as talented students.
Farzad Fatehi   +6 more
doaj  

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

open access: yesAdvanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera   +10 more
wiley   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo   +19 more
wiley   +1 more source

Detecting the effectiveness of two tools for detecting the talented from their teachers' points of view

open access: yesمجلة كلية التربية للبنات, 2019
Education specialists have differed about determining the best ways to detect the talented. Since the appearance of the mental and psychological measurement movement, some scholars adopted intelligence ratios as a criterion to identify the talented and ...
حزيمة كمال عبد المجيد
doaj  

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

open access: yesAdvanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

open access: yesAdvanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang   +18 more
wiley   +1 more source

Substitution Between Managers and Subordinates: Evidence from British Football [PDF]

open access: yes
We use data on British football managers and teams over the 1994-2007 period to study substitution and complementarity between leaders and subordinates.
Amanda H. Goodall   +2 more
core  

The Whalesong [PDF]

open access: yes, 2005
Student Senate opposes tuition fee -- Senate votes to open the Arctic National Wildlife Refuge -- Campus calendar -- Program cuts haunt budget -- Got class?

core  

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Journal of African Christian Biography: v. 2, no. 4 [PDF]

open access: yes, 2017
A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. The Martyrdom of Bernard Mizeki. 2. Bernard Mizeki. 3.
Amanze, James Nathaniel   +4 more
core  

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