Results 71 to 80 of about 3,776 (143)

Analysis of Treatment Patterns for Mucosal Melanoma Using Real‐World Data in the SEER‐Medicare–Linked Database

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Mucosal melanoma (MM) is a rare, aggressive disease, often diagnosed late, and associated with poor survival. Surgical resection is the main potential curative option, but anatomical complexity limits feasibility, and real‐world evidence on treatment patterns remains scarce.
Marjan Zakeri, Samuel Wagner, Xianxin Zhu, Onur Baser   +3 more
wiley   +1 more source

Concomitant Medication Effects on Immunotherapy Outcomes in Sarcoma: A Pooled Post Hoc Analysis of Seven Phase II Trials

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Concomitant medications (CMs) influence outcomes in patients receiving immune checkpoint inhibitors (ICIs), but their impact in sarcoma remains undefined. We assessed the association between CM use and ICI outcomes in patients with advanced or metastatic sarcoma. Methods This pooled analysis included patients from seven investigator‐
Adel Shahnam, Kristen DiConza, Simran Jasnani, Rhoena Desir‐Camille, Evan Rosenbaum, Olayode Babatunde, Ciara M. Kelly, Lauren B. Banks, Viswatej Avutu, Ping Chi, Sujana Movva, Mark A. Dickson, Mrinal M. Gounder, Mary L. Keohan, Robert G. Maki, William D. Tap, Sandra P. D'Angelo   +16 more
wiley   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, Volume 1, Issue 2, Page 63-89, June 2026.
ABSTRACT The growing recognition of the microbiome’s role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley   +1 more source

Practical clinical guide on the use of talimogene laherparepvec monotherapy in patients with unresectable melanoma in Europe

, 2018
Talimogene laherparepvec, a herpes simplex virus type 1-based intralesional oncolytic immunotherapy, is approved in Europe for the treatment of adults with unresectable stage IIIB-IVM1a melanoma, with no bone, brain, lung or other visceral disease.
Gutzmer, Ralf, Downey, Gerald, Dummer, Reinhard; https://orcid.org/, Harrington, Kevin J, Öhrling, Katarina, Hoeller, Christoph; https://orcid.org/, Malvehy, Josep; https://orcid.org/, Lebbé, Céleste; https://orcid.org/   +7 more
core   +1 more source

Induced Vitiligo due to Talimogene Laherparepvec Injection for Metastatic Melanoma Associated with Long-term Complete Response [PDF]

, 2020
Talimogene laherparepvec (T-VEC) (Imlygic, Amgen) is the first oncolytic virus approved for use in therapy for metastatic melanoma. T-VEC provides a treatment option for patients with limited metastatic disease.
Barreiro Capurro, Alicia, Podlipnik, Sebastian, Ribero, Simone, Malvehy, J. (Josep), Puig i Sardà, Susana, Iglesias, Pablo, Carrera Álvarez, Cristina   +6 more
core   +1 more source

Transcriptomic Profiling of Cutaneous Melanoma Metastases Treated With Microwave Ablation—Pilot Study

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Microwave ablation induces heating of tissue. High energy results in thermal cell death, but low energy treatment without tissue necrosis has been shown to induce cutaneous immunity in an HPV wart model. It is approved as an effective cancer treatment for solid organ cancers, and therefore it is of interest to know if microwave delivered ...
Purevsuren Losol, Daniel O'Driscoll, Andres Vallejo Pulido, Adrian von Witzleben, Konstantinos Boukas, Matthew Sommerlad, Christian Ottensmeier, Michael R. Ardern‐Jones   +7 more
wiley   +1 more source

The Immune Landscape of Acral Melanoma: From Basic to Clinical

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Acral melanoma (AM) is an aggressive melanoma subtype with poor prognosis and limited response to immune checkpoint inhibitors (ICIs). Despite increasing research efforts, the mechanisms underlying therapeutic resistance remain incompletely understood.
Lihong Jiang, Zhaotian Zhang
wiley   +1 more source

Safe and effective administration of T-VEC in a patient with heart transplantation and recurrent locally advanced melanoma

Journal for ImmunoTherapy of Cancer, 2017
Background Immunotherapy plays a key role in the treatment of metastatic melanoma. Patients with autoimmune conditions and/or on immunosuppressive therapy due to orthotropic transplants, however, are systematically excluded from clinical trials ...
Gustavo Schvartsman, Kristen Perez, Jill E. Flynn, Jeffrey N. Myers, Hussein Tawbi   +4 more
doaj   +1 more source

Biopharmaceuticals for Cancer Treatment: An Update

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath, Yousuf Alam, Afsana Mustak Mim, Maksuda Akter, Mohammad Abbas Gani, Khondaker Muhammad Khairul Alam, Md. Nur Alam   +6 more
wiley   +1 more source