Results 101 to 110 of about 1,432,264 (297)
Technology readiness and segmentation profile of mature consumers [PDF]
, 2010 Self-service technologies (SSTs) play a major role in enabling consumers to perform service delivery themselves. The purpose of this study was to test extensions of the original Technology Acceptance Model (TAM) aimed at predicting mature consumers ...
Fogarty, Gerard J., Rose, Janelle
core
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundAscending aortic pseudoaneurysm is a rare but potentially fatal complication after aortic surgery, particularly challenging in elderly high-risk patients.Case presentationWe report an 80-year-old man with a history of surgical repair for acute ...
Phuc Nang Vu +6 more
doaj +1 more source
Advanced Science, EarlyView.This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source
Conscious Indirect Blood Pressure Measurements in Asiatic Black Bears (Ursus thibetanus)
AnimalsAt Animals Asia’s Vietnam Bear Rescue Center (VBRC), 40% of the current population has been diagnosed with systemic hypertension. Systemic hypertension lesions have led to fatal consequences in the form of aortic aneurysm and rupture.
Grace M. Scrafford +4 more
doaj +1 more source
AN ANALYSIS OF THE ACCEPTANCE OF LOOT BOXES USING THE MODIFIED TECHNOLOGY ACCEPTANCE MODEL: THE EMPIRICAL EVIDENCE FROM VIDEO GAME PLAYERS IN SERBIA [PDF]
Economic HorizonsBusiness models in the video game industry have shifted from physical to digital. With microtransactions, game producers have been provided with the ability to charge for extra in-game content.
Nenad Tomić, Marija Mirić
doaj +1 more source
Dynamic test/analysis correlation using reduced analytical models [PDF]
Test/analysis correlation is an important aspect of the verification of analysis models which are used to predict on-orbit response characteristics of large space structures.
Angelucci, A. Filippo +2 more
core +1 more source
Advanced Science, EarlyView.This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou +9 more
wiley +1 more source
Salient Object Detection via Augmented Hypotheses [PDF]
, 2015 In this paper, we propose using \textit{augmented hypotheses} which consider objectness, foreground and compactness for salient object detection. Our algorithm consists of four basic steps.
Nguyen, Tam V., Sepulveda, Jose
core +2 more sources
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source