Results 81 to 90 of about 1,418,713 (273)

Double-Bundle Anterior Cruciate Ligament Repair and Augmentation With Lateral Extra-articular Tenodesis

Arthroscopy Techniques
The evidence to date still favors anterior cruciate ligament (ACL) reconstruction over anterior cruciate ligament repair because ACL repair has a higher failure rate.
Nguyen Quang Ton Quyen, M.D., Duong Minh Hieu, M.D., Vu Trung Hieu, M.D., Pham Ngoc Thang, M.D., Ph.D., Tang Ha Nam Anh, M.D., Ph.D.   +4 more
doaj   +1 more source

The Construction of the Past: Towards a Theory for Knowing the Past

Information, 2019
This paper presents Constructed Past Theory, an epistemological theory about how we come to know things that happened or existed in the past. The theory is expounded both in text and in a formal model comprising UML class diagrams.
Kenneth Thibodeau
doaj   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

The dark matter in cancer immunology: beyond the visible– unveiling multiomics pathways to breakthrough therapies

Journal of Translational Medicine
Cancer cells orchestrate the surrounding tumor microenvironment (TME) to strike a fine balance between tissue regeneration providing them with nutrients, and tissue destruction triggered by immunogenic alarm signals.
Salvatore De Rosis, Gianni Monaco, Joyce Hu, Erik Hett, Rosamaria Lappano, Francesco M Marincola, Ali Asadi, Marcello Maggiolini   +7 more
doaj   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Remnant Preservation Anterior Cruciate Ligament Reconstruction: Modified All-Inside Technique With Appendiceal Tibial Tunnel

Arthroscopy Techniques
The number of anterior cruciate ligament (ACL) ruptures treated arthroscopically has increased. In most cases, the rupture of the ligament occurs in the femoral attachment, leaving a robust stump attached to the tibia.
An Van Duy Ho, M.Sc., M.D., Khoa Dinh Le, M.Sc., M.D., Thanh Nhat Le, M.Sc., M.D., Vu Anh Tran, M.Sc., M.D., Anh Ha Nam Tang, Ph.D., M.D.   +4 more
doaj   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Esophageal achalasia compressing the left atrium and mimicking an extracardiac tumor on the transthoracic echocardiography: A case report

Radiology Case Reports
Achalasia is an uncommon disorder affecting esophageal motility. Occasionally, the appearance of a dilated esophagus in achalasia may resemble an extracardiac tumor when observed through transthoracic echocardiography.
Khoa Le, MD, Thuy Pham, MD, Cuong Ho, MD, Truc Tran, MD, Vinh Pham, PhD, Phuc Vu, MD   +5 more
doaj   +1 more source

Drivers of Pre-service and In-service Teachers’ Acceptance and Integration of Emerging Technologies into Pedagogical Practices [PDF]

Educaţia 21
The rate of development of educational technologies has implications not only for the technical capacity of an educational institution to provide hardware and software solutions for the existing learning environment, but also for pedagogical practices ...
Nadia Barkoczi, Alina Felicia Roman, Monica Laura Maier   +2 more
doaj   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source