Results 131 to 140 of about 122,604 (290)
, 2016 (A) LCMV naive UBC-Cre-ERT2+IFNαβRfl/fl and UBC-Cre-ERT2-IFNαβRfl/fl mice were injected with tamoxifen and ~9 weeks later were given a primary infection with LCMV.
J. Lindsay Whitton (44261) +2 more
core +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective Up to 14% of women with early‐stage endometrial carcinoma (EEC) are diagnosed before menopause. Although ovarian preservation (OP) within surgical staging might avoid surgical menopause, its rate remains low in clinical practice, probably because the impact of OP on survival outcomes is unclear.
Antonio Raffone +12 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a syndrome characterized by fragility fractures (most commonly vertebral, often multiple) occurring in late pregnancy or the early postpartum period. This position statement summarizes the current knowledge of PLO, and the recommended procedure for assessment, diagnosis and treatment ...
Peyman Hadji +20 more
wiley +1 more source
, 2015 Objectives To compare the effects of tamoxifen and raloxifene on the proliferative activity of normal breast tissue in premenopausal women as measured by Ki-67/MIB-1 expression.
Marise A. R. Moreira +6 more
core +1 more source
Multi‐omics–driven precision medicine
iMeta, EarlyView.Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
Drug-induced liver injury secondary to tamoxifen
Tamoxifen is a non-steroidal selective oestrogen receptor modulator commonly used in the treatment of breast cancer. It is associated with the development of fatty liver and steatohepatitis however drug-induced liver injury is rare.
Murphy, Grace +3 more
core +1 more source
Interdisciplinary Medicine, EarlyView.Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang +22 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao +7 more
wiley +1 more source
Periodontitis and breast cancer risk: A systematic review with meta‐epidemiological analysis
Journal of Periodontology, EarlyView.Abstract Background The association between periodontitis and breast cancer (BC) risk has been reported, but with considerable variability in effect estimates across studies. This meta‐epidemiological study aimed to systematically evaluate how methodological characteristics of primary studies influence these reported effect estimates.
Rhayssa Kuhn Peitoxo +5 more
wiley +1 more source