Results 161 to 170 of about 113,809 (305)
CYP2D6 polymorphisms influence the efficacy of adjuvant tamoxifen in Thai breast cancer patients
, 2012 Ekaphop Sirachainan,1 Sureerat Jaruhathai,1 Narumol Trachu,2 Ravat Panvichian,1 Thitiya Sirisinha,1 Touch Ativitavas,1 Vorachai Ratanatharathorn,1 Montri Chamnanphon,3 Chonlaphat Sukasem31Division of Medical Oncology, Department of Medicine, 2Research ...
Ativitavas T +8 more
core
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
Risk of Cancer With Hormone Replacement Therapy: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue +3 more
wiley +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source
Effect of Allicin on Tamoxifen-sensitive MCF-7 Breast Cancer Cells
Journal of Medicinal Plants, 2015 Background: One-eighth of women will develop breast cancer in their lifetime, resulting in approximately annual one million women worldwide with breast cancer. Approximately 70% of breast cancers are positive for estrogen receptor alpha (ER-).
P Rahimi-Moghaddam +2 more
doaj
Integrative Zoology, EarlyView.The increase in salinity leads to changes in the gut microbiota and metabolites of Trachemys scripta elegans, affecting the synthesis and secretion of neurotransmitters or precursors, which can inhibit the secretion of reproductive hormones and affect the self‐renewal and differentiation process of spermatogonial stem cells.
Qiongyu Zhang +5 more
wiley +1 more source
Early detection of tamoxifen-induced retinal injury: ellipsoid zone reflectivity as a sensitive structural marker. [PDF]
BMC OphthalmolUnlu BH +3 more
europepmc +1 more source
, 2006 Summary The effect of tamoxifen citrate on bone mass in immobilization osteoporosis was studied in 10 dogs. Osteoporosis was induced by fiberglass cast immobilization of the right hind-limb for 28 days, while the left hind-limb served as a non ...
Saifzadeh, Siamak +3 more
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Asia-Pacific Journal of Clinical Oncology, EarlyView.This retrospective study of patients with small, node‐negative HER2+ breast cancer found favorable 5‐year invasive disease‐free survival rates—93% for pT1mic/a disease and 100% for pT1b disease. Trastuzumab was administered to 66% of patients and was associated with larger tumor size and higher histologic grade.
Yuanyuan Xue +5 more
wiley +1 more source
Evaluating the synergistic effects of cisplatin and tamoxifen in canine osteosarcoma cells. [PDF]
Front Vet SciMays M, Tanner K, Lugo T, Nguyen TA.
europepmc +1 more source