Results 101 to 110 of about 70,211 (203)

Drug Efflux Transporters Are Overexpressed in Short-Term Tamoxifen-Induced MCF7 Breast Cancer Cells

Advances in Pharmacological Sciences, 2016
Tamoxifen is the first line drug used in the treatment of estrogen receptor-positive (ER+) breast cancer. The development of multidrug resistance (MDR) to tamoxifen remains a major challenge in the treatment of cancer.
Desak Gede Budi Krisnamurti, Melva Louisa, Erlia Anggraeni, Septelia Inawati Wanandi   +3 more
doaj   +1 more source

Ron Receptor Tyrosine Kinase Activation Confers Resistance to Tamoxifen in Breast Cancer Cell Lines

Neoplasia: An International Journal for Oncology Research, 2010
Although tamoxifen treatment is associated with improved survival in patients with estrogen receptor (ER)-positive breast tumors, resistance remains an important clinical obstacle. Signaling through growth factor signaling pathways, in particular through
Rebecca J. McClaine, Aaron M. Marshal, Purnima K. Wagh, Susan E. Waltz   +3 more
doaj   +1 more source

Tamoxifen treatment causes early hepatic insulin resistance [PDF]

Acta Diabetologica, 2020
Klöting, N., Kern, M., Moruzzi, M., Stumvoll, M., Blüher, M.   +4 more
openaire   +3 more sources

Role of transforming growth factor receptor beta I type in the progression of the luminal breast cancer subtype [PDF]

, 2017
Identification of additional biomarkers that are able to predict prognosis and treatment response may be very useful to distinguish patients who will benefit from tamoxifen treatment.
Дронова, Т. А.
core  

Exposure to polybrominated diphenyl ethers (PBDEs) suppresses the release of pro-inflammatory products by alveolar macrophages in vitro [PDF]

, 2010
Endocrine disrupting chemicals have adverse effects on immune function that may result in respiratory conditions. Inhalation of dust is a major route of exposure to PBDEs; however, the impact of PBDEs on the immune response is unclear.
Hennigar, Stephen R
core   +1 more source

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. [PDF]

, 2018
Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension ...
Ayon, Ramon J, Balistrieri, Angela, Black, Stephen M, Chen, Jiwang, Desai, Ankit A, Garcia, Joe GN, Gu, Yali, Makino, Ayako, Rischard, Franz, Song, Shanshan, Tang, Haiyang, Vanderpool, Rebecca, Vinjamuri, Sujana, Wang, Jian, Wang, Ziyi, Wu, Kang, Yuan, Jason X-J, Zhang, Qian, Zhou, Guofei   +18 more
core   +1 more source

Mammalian enabled protein enhances tamoxifen sensitivity of the hormone receptor-positive breast cancer patients by suppressing the AKT signaling pathway

Biology Direct
Background Mammalian enabled (MENA) protein is a member of the enabled/vasodilator stimulated phosphoprotein (Ena/VASP) protein family, which regulates cytoplasmic actin network assembly.
Lifang He, Chuanghong She, Sen Jiang, Zhaochang Qi, Zihao Deng, Likeng Ji, Yukun Cui, Jundong Wu   +7 more
doaj   +1 more source

Deletion of Cardiac miR-17-92 Cluster Increases Ischemia/ Reperfusion Injury via PTEN Upregulation [PDF]

, 2017
The miR-17- 92 cluster is necessary for cell proliferation and development of the cardiovascular system. Deletion of this cluster leads to death in neonatal mice.
Prakash, Meeta B
core   +1 more source

Focal Spot, Fall/Winter 1998 [PDF]

, 1998
https://digitalcommons.wustl.edu/focal_spot_archives/1080/thumbnail ...

core   +1 more source

EGR3 and estrone are involved in the tamoxifen resistance and progression of breast cancer. [PDF]

J Cancer Res Clin Oncol, 2023
Xie Y, Han X, Yu J, Yuan M, Yan Y, Qin J, Lan L, Wang Y.   +7 more
europepmc   +1 more source