Results 161 to 170 of about 2,242,189 (260)

The EGR1/caspase-14/HIF-1α axis mediates tamoxifen resistance in MCF-7 breast cancer cells. [PDF]

Open Life Sci
Ji F, Zhao A, Chen Q, Li C, Huang L.
europepmc   +1 more source

ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer. [PDF]

Epigenetics, 2023
Kim HW, Baek M, Jung S, Jang S, Lee H, Yang SH, Kwak BS, Kim SJ.   +7 more
europepmc   +1 more source

4‐Hydroxytamoxifen induces a noncanonical ferroptosis in lung adenocarcinoma by targeting AKR1B10

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
4‑OHT directly inhibits AKR1B10 enzymatic activity to induce noncanonical ferroptosis in LUAD. AKR1B10 sustains LUAD survival by stabilising ACC1 and detoxifying reactive carbonyl species (RCSs). Nanatinostat similarly targets AKR1B10 and elicits the same cell death modality.
Hui Yang, Yanan Wang, Jiangbo Jin, Hanyan Xu, Yinshui Miao, Xiaojing Wu, Shengsong Chen, Tianyu Han, Qingyuan Zhan   +8 more
wiley   +1 more source

BMP1 Appears to be Involved in GPER1-mediated Progression and Tamoxifen Resistance of Luminal A Breast Cancer Cells. [PDF]

Cancer Genomics Proteomics
Wert K, Jentsch J, Gallwas J, Gründker C.   +3 more
europepmc   +1 more source

A TREK‐1/AQP4/TRPA1/BDNF Signaling Axis Is Associated With Astrocytic Volume Transients, Synaptic Plasticity, and Spatial Memory

Glia, Volume 74, Issue 9, September 2026.
Astrocytic TREK‐1‐dependent volume transients contribute to hippocampal synaptic plasticity and memory formation. TRPA1‐mediated astrocytic calcium signaling is required for long‐term potentiation, while astrocytic BDNF is necessary and sufficient to support sustained synaptic plasticity.
Victor James Drew, Junsung Woo, Jung Moo Lee, Wuhyun Koh, Joungha Won, Jae‐Hun Lee, C. Justin Lee   +6 more
wiley   +1 more source

Genetic and epigenetic contribution to tamoxifen resistance in breast cancer, concepts to drive therapeutic strategies. [PDF]

Discov Oncol
Jahangiri R.
europepmc   +1 more source

circRNA-SFMBT2 orchestrates ERα activation to drive tamoxifen resistance in breast cancer cells. [PDF]

Cell Death Dis, 2023
Li Z, Li Y, Han D, Wang X, Li C, Chen T, Li W, Liang Y, Luo D, Chen B, Wang L, Zhao W, Yang Q.   +12 more
europepmc   +1 more source

Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis

Glia, Volume 74, Issue 9, September 2026.
Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning, Ioannis Zalachoras, Giovanni Carriero, Gerald Seifert, Peter Bedner, Christian Steinhäuser, Andrea Volterra   +6 more
wiley   +1 more source

Hsa_circ_0062522 affects the progression and tamoxifen resistance of estrogen receptor-positive breast cancer by targeting miR-3163. [PDF]

Discov Oncol
Bian Y, Ma Y, Xu Y, Mao J, Huang L.
europepmc   +1 more source

Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age

International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1151-1171, September 2026.
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho, Suvarna Khadilkar, Hema Divakar, Chiara Benedetto, Andrea R. Genazzani, Diana Ramos, Elizabete Argale, Enrique Herrera, Martha Hickey   +8 more
wiley   +1 more source