Results 91 to 100 of about 537,118 (341)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Collaborative reading and foreign language learning with literature

Journal of Virtual Exchange
Teletandem is a virtual exchange context designed by Telles and Vassallo (2006), in which two learners of different foreign languages meet in video conferencing platforms so that one helps the other in their learning process.
Vanessa Matiola
doaj   +1 more source

Tandem-win graphs

Discrete Mathematics, 2005
AbstractIn this version of the Cops and Robber game, the cops move in tandems, or pairs, such that they are at distance at most one after every move. We present a recognition theorem for tandem-win graphs, and a characterization of triangle-free tandem-win graphs.
Nancy E. Clarke, Richard J. Nowakowski
openaire   +2 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The potential of IT tools in foreign language acquisition: A comparative assessment [PDF]

Training, Language and Culture
The integration of information technology (IT) in foreign language education has transformed traditional methodologies, yet challenges persist in optimising their application.
Lazar Stošić, Francisco David Guillén-Gámez   +1 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

La télécollaboration vue par la communication exolingue – Pour un enrichissement mutuel de deux traditions de recherche

ALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2017
This article discusses the possible relationship between research on telecollaboration and research on exolingual communication, in order to show how studies in these two fields could potentially complement each other.
Marco Cappellini
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Correction of nocturia in patients with benign prostatic hyperplasia. Mini-review and analysis of clinical observations

Consilium Medicum
Aim. To outline the importance of nocturia in benign prostatic hyperplasia (BPH) and justify the feasibility and clinical need for antidiuretic therapy in these patients. Materials and methods. This article is a literature review.
Igor A. Tyuzikov
doaj   +1 more source

Tournant social des dispositifs d'apprentissage des langues en autoformation – Un exemple de dispositif pour le russe

ALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2019
Nous proposons dans cet article de présenter un dispositif institutionnel d'apprentissage en autoformation du russe au Cnam, adapté d'un dispositif d'autoformation en langues implanté il y a 30 ans dans le même établissement.
Elsa Chachkine
doaj   +1 more source