Results 131 to 140 of about 348,025 (296)

TanDEM-X Experiments in Pursuit Monostatic Configuration [PDF]

, 2012
This paper reports on several experiments performed by the TanDEM-X constellation that could be potentially implemented as operational modes in future SAR missions.
Steinbrecher, Ulrich, Wollstadt, Steffen, Baumgartner, Stefan, Krieger, Gerhard, Schulze, Daniel, Mittermayer, Josef, Zink, Manfred, Moreira, Alberto, Prats, Pau, Reigber, Andreas, Scheiber, Rolf, López-Dekker, Francisco, Rodríguez-Cassolà, Marc   +12 more
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Real‐World Outcomes of Midostaurin Plus Intensive Chemotherapy in FLT3‐Mutated AML: The PETHRATIFY Study

American Journal of Hematology, EarlyView.
ABSTRACT Mutations in FLT3 are present in approximately 30% of patients with AML. The addition of midostaurin (MIDO) to intensive chemotherapy (IC) became standard of care following the RATIFY trial, but comprehensive real‐world data spanning the full adult age spectrum and including both FLT3‐ITD and FLT3‐TKD mutations remain limited.
Mónica Alejandra Romero Riquelme, Gaspar Aspas Requena, Pilar Lloret‐Madrid, Cristina Gil, Eliana Aguiar, Mar Tormo, Teresa del Bernal del Castillo, Eduardo Rodríguez Arbolí, Josefina Serrano, Joaquín Sánchez‐García, Carlos Rodríguez‐Medina, José Mário Mariz, Rosa Ayala, Joaquín Martínez‐López, María Luz Amigo, Susana Vives, Lorenzo Algarra Algarra, Raimundo García Boyero, Joana Brioso, Tamara Castaño, Juan M. Bergua Burgués, Olga Salamero, María Francisca Bass Maturana, Mercedes Colorado, María García Fortes, María José Sayas Lloris, Belén Vidriales Vicente, Carmen Chillón, Esther Pérez Santaolalla, María Dolores Madrigal, Jorge Labrador Gómez, María José García Pérez, Soledad Casado Calderón, Manuel Pérez Encinas, Amaia Balerdi Malcorra, María Solé Rodríguez, Lara María Gómez García, Pilar Herrera Puente, Olga Arce Fernández, Manuel Barrios García, Víctor Noriega, Rosa Fernández, Mamen Mateos, Carolina Lacalzada, Ágata Almela Gallego, María Carmen García Garay, Carmen Couto, José Antonio Pérez‐Simón, Eva Barragán González, Pau Montesinos   +49 more
wiley   +1 more source

An interstitial tandem duplication of 9p23-24 coexists with a mutation in the BRCA2 gene in the germ line of three brothers with breast cancer

, 1998
Germ-line mutations of the BRCA2 gene account for the majority of families with both male and female breast cancer. However, among independently ascertained families with the same mutation, cases of male breast cancer often appear to cluster in a single ...
Stratton, M.R., Schwab, M., Schlag, P.M., Finke, L., Savelyeva, L., Claas, A., Gier, S., Mangion, J.   +7 more
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Expanding the Utility of Exome Sequencing in Preventive and Population Genetics

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Carrier screening is a long‐standing genetic testing process offered to at‐risk couples, with or without a family history, who might have pregnancies affected by an autosomal recessive (AR) or X‐linked (XL) disorder. A total of 276 unrelated individuals, initially referred for rare disorder screening by clinicians, were enrolled in this study ...
Charilaos Kostoulas, Athanasia Sesse, Ioanna Bouba, Robert Najdecki, Spyridon Konitsiotis, Sofia Markoula, Ioannis Georgiou   +6 more
wiley   +1 more source

TanDEM-X: A High Resolution Radar Topography Mission [PDF]

, 2011
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer that is based on two high-resolution radar satellites in close formation flight: TerraSAR-X (launched on June 15, 2007) and TanDEM-X ...
Moreira, Alberto
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The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Mechanism of tandem duplication formation in BRCA1-mutant cells.

, 2017
Small, approximately 10-kilobase microhomology-mediated tandem duplications are abundant in the genomes of BRCA1-linked but not BRCA2-linked breast cancer. Here we define the mechanism underlying this rearrangement signature.
E. Paul Hasty, Panday, Arvind, Liu, Edison T, Willis, Nicholas A, Duffey, Erin E, Camacho, Virginia, Erin E. Duffey, Richard L. Frock, Alt, Frederick W, Francesca Menghi, Edison T. Liu, Hasty, E Paul, Scully, Ralph, Ralph Scully, Arvind Panday, Virginia Camacho, Frock, Richard L, Frederick W. Alt, Menghi, Francesca, Nicholas A. Willis   +19 more
core   +1 more source

Mutations in the dwarf3 gene confer height stability in sorghum

The Plant Genome
Dwarfism is a useful trait in many crop plants because it contributes to improved lodging resistance and harvest index. The mutant allele dw3‐ref (dwarf3‐reference) of sorghum [Sorghum bicolor (L.) Moench] is characterized by an 882 bp tandem duplication
Elisabeth Diatta‐Holgate, Ben Bergsma, Mitchell R. Tuinstra   +2 more
doaj   +1 more source

TanDEM-X Scientific Results and Future Formation Flying SAR Missions [PDF]

, 2011
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that was launched on June 21, 2010. This paper gives an overview of scientific experiments that have been conducted during the TanDEM-
Lopez Dekker, Paco, De Zan, Francesco, Hajnsek, Irena, Rodriguez Cassola, Marc, Zink, Manfred, Moreira, Alberto, Prats, Pau, Baumgartner, Stefan, Papathanassiou, Konstantinos, Krieger, Gerhard   +9 more
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