Results 41 to 50 of about 671,203 (335)

Comparative Analysis Reveals Different Evolutionary Fates and Biological Functions in Wheat Duplicated Genes (Triticum aestivum L.)

Plants, 2023
Wheat (Triticum aestivum L.) is a staple food crop that provides 20% of total human calorie consumption. Gene duplication has been considered to play an important role in evolution by providing new genetic resources.
Licao Cui, Hao Cheng, Zhe Yang, Chuan Xia, Lichao Zhang, Xiuying Kong   +5 more
doaj   +1 more source

A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior [PDF]

, 2015
Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Borevitz, Justin O., Distler, Margaret G., Harr, Bettina, Lim, Jackie E., Palmer, Abraham A., Sokoloff, Greta, Su, Andrew I., Tarantino, Lisa M., Teschke, Meike, Walters, Ryan, Williams, Richard, Wiltshire, Tim, Wing, Claudia, Wu, Chunlei   +13 more
core   +2 more sources

Host plant-dependent phenotypic reversion of Ralstonia solanacearum from non-pathogenic to pathogenic forms via alterations in the phcA gene [PDF]

, 2003
Ralstonia solanacearum is a plant pathogenic bacterium that undergoes a spontaneous phenotypic conversion (PC) from a wild-type pathogenic to a non-pathogenic form.
Arlat, Mathieu, Barthet, Séverine, Meyer, Damien, Poussier, Stéphane, Thoquet, Philippe, Trigalet Démery, Danièle, Trigalet, André   +6 more
core   +1 more source

Greedy method for inferring tandem duplication history [PDF]

Bioinformatics, 2003
Abstract Motivation: Genome analysis suggests that tandem duplication is an important mode of evolutionary novelty by permitting one copy of each gene to drift and potentially to acquire a new function. With more and more genomic sequences available, reconstructing duplication history has received extensive attention recently.
Zhang, L., Ma, B., Wang, L., Xu, Y.
openaire   +2 more sources

Phase I study of sorafenib in patients with refractory or relapsed acute leukemias

Haematologica, 2011
Background Sorafenib is a multi-kinase inhibitor with activity against fms-like tyrosine kinase 3 with internal tandem duplication mutation and Raf kinase among others.
Gautam Borthakur, Hagop Kantarjian, Farhad Ravandi, Weiguo Zhang, Marina Konopleva, John J. Wright, Stefan Faderl, Srdan Verstovsek, Sheela Mathews, Michael Andreeff, Jorge E. Cortes   +10 more
doaj   +1 more source

A case of recurrent epilepsy-associated rosette-forming glioneuronal tumor with anaplastic transformation in the absence of therapy. [PDF]

, 2019
Rosette-forming glioneuronal tumor (RGNT) most commonly occurs adjacent to the fourth ventricle and therefore rarely presents with epilepsy. Recent reports describe RGNT occurrence in other anatomical locations with considerable morphologic and genetic ...
Corless, Christopher L, Ferris, Sean P, Grafe, Marjorie, Gultekin, Sakir H, Halfpenny, Aaron, Lawce, Helen, Lucas, Lora, Moore, Stephen, Nazemi, Kellie, Olson, Susan, Perry, Arie, Selden, Nathan, Solomon, David A, Woltjer, Randy, Wood, Matthew D   +14 more
core   +1 more source

The impact of genome triplication on tandem gene evolution in Brassica rapa

Frontiers in Plant Science, 2012
Whole genome duplication (WGD) and tandem duplication (TD) are both important modes of gene expansion. However, how whole genome duplication influences tandemly duplicated genes is not well studied.
Lu eFang, Feng eCheng, Jian eWu, Xiaowu eWang   +3 more
doaj   +1 more source

The capacity of some Pólya string models [PDF]

, 2016
We study random string-duplication systems, called Pólya string models, motivated by certain random mutation processes in the genome of living organisms.
Bruck, Jehoshua, Elishco, Ohad, Farnoud, Farzad, Schwartz, Moshe   +3 more
core   +1 more source

High‐grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication—a comprehensive clinical, radiographic, pathologic, and genomic analysis

Brain Pathology, 2019
High‐grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication (HGNET BCOR ex15 ITD) is a recently proposed tumor entity of the central nervous system (CNS) with a distinct methylation profile and characteristic genetic alteration.
S. Ferris, José E. Velázquez Vega, M. Aboian, Julieann C Lee, J. Van Ziffle, C. Onodera, J. Grenert, T. Saunders, Yunni-Yi Chen, A. Banerjee, C. Kline, N. Gupta, C. Raffel, David Samuel, I. Ruiz-Díaz, Shino Magaki, D. Wilson, J. Neltner, Zahra Al-Hajri, J. Phillips, M. Pekmezci, A. Bollen, T. Tihan, M. Schniederjan, S. Cha, A. Perry, D. Solomon   +26 more
semanticscholar   +1 more source

Characterization and Expression Analysis of ERF Genes in Fragaria vesca Suggest Different Divergences of Tandem ERF Duplicates

Frontiers in Genetics, 2019
Ethylene-responsive factors (ERFs) play important roles in plant growth and development and in responses to abiotic stresses. However, little information was available about the ERF genes in woodland strawberry (Fragaria vesca), a genetic model plant for
Xiaojing Wang, Shanshan Lin, Decai Liu, Quanzhi Wang, Richard McAvoy, Jing Ding, Yi Li, Yi Li   +7 more
doaj   +1 more source