Mobile Image Ratiometry: A New Method for Instantaneous Analysis of Rapid Test Strips [PDF]
, 2012 Here we describe Mobile Image Ratiometry (MIR), a new method for the automated quantification of standardized rapid immunoassay strips using consumer-based mobile smartphone and tablet cameras.
Bryan Callahan +3 more
core +2 more sources
SIRIUS 4: a rapid tool for turning tandem mass spectra into metabolite structure information
Nature Methods, 2019 Mass spectrometry is a predominant experimental technique in metabolomics and related fields, but metabolite structural elucidation remains highly challenging.
Kai Dührkop +8 more
semanticscholar +1 more source
Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast
STAR Protocols, 2021 Summary: Here, we describe a fractionation protocol optimized to quantify changes in relative abundance of the chromatin-bound proteome (chromatome) by tandem mass tag multiplexing-based tandem mass spectrometry. It has been applied to yeast cells before
Kiran Challa +2 more
doaj
Elucidation of Nucleic Acid–Drug Interactions by Tandem Mass Spectrometry
CHIMIA, 2014 In continuation of the long tradition of mass spectrometric research at the University of Bern, our group focuses on the characterization of nucleic acids as therapeutic agents and as drug targets.
Yvonne Hari +3 more
doaj +1 more source
Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics. [PDF]
, 2019 Inborn errors of metabolism (IEMs) are a group of inherited diseases with variable incidences. IEMs are caused by disrupting enzyme activities in specific metabolic pathways by genetic mutations, either directly or indirectly by cofactor deficiencies ...
Fiehn, Oliver +2 more
core +2 more sources
Postanalytical tools improve performance of newborn screening by tandem mass spectrometry
Genetics in Medicine, 2014 Purpose:The purpose of this study was to compare performance metrics of postanalytical interpretive tools of the Region 4 Stork collaborative project to the actual outcome based on cutoff values for amino acids and acylcarnitines selected by the ...
P. Hall +6 more
semanticscholar +1 more source
Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]
, 2003 In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Schiel, Xaver +2 more
core +1 more source
Liquid Chromatography Electron Capture Dissociation Tandem Mass Spectrometry (LC-ECD-MS/MS) versus Liquid Chromatography Collision-induced Dissociation Tandem Mass Spectrometry (LC-CID-MS/MS) for the Identification of Proteins [PDF]
, 2007 Electron capture dissociation (ECD) offers many advantages over the more traditional fragmentation techniques for the analysis of peptides and proteins, although the question remains: How suitable is ECD for incorporation within proteomic strategies for ...
A. G. Marshall +38 more
core +4 more sources
RAId DbS: A Mass-Spectrometry Based Peptide Identification Web Server with Knowledge Integration [PDF]
arXiv, 2008 Summary: In anticipation of the individualized proteomics era and the need to integrate knowledge from disease studies, we have augmented our peptide identification software RAId DbS to take into account annotated single amino acid polymorphisms, post-translational modifications, and their documented disease associations while analyzing a tandem mass ...
arxiv
An on-line solid phase extraction procedure for the routine quantification of caspofungin by liquid chromatography-tandem mass spectrometry [PDF]
, 2012 Background: Extensive sets of data are required to investigate the potential use of a therapeutic drug monitoring with individualization of dosage of the antimycotic compound caspofungin.
Kirchhoff, Fabian +5 more
core +1 more source