Results 241 to 250 of about 988,611 (339)

Dynamic Ionic Environment Modulation for Precise Electrosynthesis of Heterostructured Bimetallic Nanoparticles

open access: yesAdvanced Science, EarlyView.
An electrosynthesis method is introduced for fabricating heterostructured bimetallic nanoparticles, providing precise and independent control over elemental distribution within individual nanostructures. By dynamically modulating the ionic environment in a dual‐channel nanopipette using scanning electrochemical cell microscopy, core–shell nanoparticles
Heekwon Lee   +3 more
wiley   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

open access: yesAdvanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu   +13 more
wiley   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

open access: yesAdvanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen   +12 more
wiley   +1 more source

Quantitative Analysis of Phytosterols in Edible Oils Using APCI Liquid Chromatography–Tandem Mass Spectrometry

open access: yesLipids, 2013
S. Mo   +5 more
semanticscholar   +1 more source

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun   +10 more
wiley   +1 more source

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