Results 241 to 250 of about 955,547 (405)

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon

Advanced Science, EarlyView.
The quantum dot integrated real‐time ELISA or QIRT‐ELISA system integrates a bead‐based quantum dot‐mediated immunoassay (BQI) with a modular microfluidic system to continuously monitor insulin and glucagon in whole blood samples and in a multiplexed setting.
Hesam Abouali, Sanjana Srikant, Md Fahim Al Fattah, Nicole G. Barra, Darryl Chan, Dayan Ban, Jonathan D. Schertzer, Mahla Poudineh   +7 more
wiley   +1 more source

Tandem Mass Spectrometry

Definitions, 2018
Troy J. Attard, Melissa D. Carter, Mengxuan Fang, Rudolph C. Johnson, G. E. Reid   +4 more
semanticscholar   +1 more source

SimMS: a GPU-accelerated cosine similarity implementation for tandem mass spectrometry. [PDF]

Bioinformatics
Onoprishvili T, Yuan JH, Petrov K, Ingalalli V, Khederlarian L, Leuchtenmuller N, Chandra S, Duarte A, Bender A, Gloaguen Y.   +9 more
europepmc   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang, Xueying Wang, Shanhong Lu, Yan Gao, Gangcai Zhu, Guo Li, Zongnan Yu, Junwei Hou, Helei Yan, Wenhui Yuan, Xin Zhang, Mien‐Chie Hung, Zhifeng Liu, Yong Liu   +13 more
wiley   +1 more source

Resolving Early Targets and Metabolomic Profile of Congenital Heart Disease Through Tandem Mass Spectrometry Screening in Neonates. [PDF]

J Am Heart Assoc
Zhang J, Jiang W, Li D, Jia W, Wu D, Yang R, Xu W, Shu Q.   +7 more
europepmc   +1 more source

Analysis of Mitochondrial Fatty Acid Oxidation Intermediates by Tandem Mass Spectrometry from Intact Mitochondria Prepared from Homogenates of Cultured Fibroblasts, Skeletal Muscle Cells, and Fresh Muscle [PDF]

, 2002
Tiina Tyni, Morteza Pourfarzam, Douglass M. Turnbull   +2 more
openalex   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

Correlations of Free Thyroid Hormones Measured by Tandem Mass Spectrometry and Immunoassay in Dogs. [PDF]

Animals (Basel)
Sasso R, Siniscalchi M, d'Ingeo S, Ventriglia G, Bitetto C, Quaranta A.   +5 more
europepmc   +1 more source

Separation, identification and quantitation of ceramides in human cancer cells by liquid chromatography–electrospray ionization tandem mass spectrometry [PDF]

, 2002
Marianne Fillet, Jean - Claude Van Heugen, Anne‐Catherine Servais, J. De Graeve, Jacques Crommen   +4 more
openalex   +1 more source

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

Advanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu, Shumin Li, Jiaji Wu, Shumin Xu, Mo Shen, Chenyang Wang, Lundqvist Andreas, Jianghao Yu, Zhiyong Xu, Yueli Shi, Nana Liu, Yunke Yang, Jiangnan Zhao, Ying Yang, Pingli Wang, Peng Yi, Jin Cheng, Junhui Sun, Mengshu Li, Peng Xiao, Kai Wang   +20 more
wiley   +1 more source