Results 21 to 30 of about 3,585,745 (304)

Water Circulation and Marine Environment in the Antarctic Traced by Speciation of 129I and 127I

Scientific Reports, 2017
Emissions of anthropogenic 129I from human nuclear activities are now detected in the surface water of the Antarctic seas. Surface seawater samples from the Drake Passage, Bellingshausen, Amundsen, and Ross Seas were analyzed for total 129I and 127I, as ...
Shan Xing, Xiaolin Hou, Ala Aldahan, Göran Possnert, Keliang Shi, Peng Yi, Weijian Zhou   +6 more
doaj   +1 more source

Automated processing of whole blood samples for the determination of immunosuppressants by liquid chromatography tandem-mass spectrometry [PDF]

, 2006
Background: Liquid chromatography tandem-mass spectrometry (LC-MS/MS) is an efficient technology for routine determination of immunosuppressants in whole blood; however, time-consuming manual sample preparation remains a significant limitation of this ...
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

Improved mass accuracy for tandem mass spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2005
With the emergence of top-down proteomics, the ability to achieve high mass measurement accuracy on tandem MS/MS data will be beneficial for protein identification and characterization. (FT-ICR) Fourier transform ion cyclotron resonance mass spectrometers are the ideal instruments to perform these experiments with their ability to provide high ...
Kaiser, Nathan K., Anderson, Gordon A., Bruce, James E.   +2 more
openaire   +2 more sources

Cluster secondary ion mass spectrometry microscope mode mass spectrometry imaging [PDF]

, 2013
RATIONALE: Microscope mode imaging for secondary ion mass spectrometry is a technique with the promise of simultaneous high spatial resolution and high-speed imaging of biomolecules from complex surfaces.
Jungmann, JH, Kiss, A., Heeren, R.M.A., Afd Scheikunde Algemeen, Smith, D.F., Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics   +6 more
core   +1 more source

Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast

STAR Protocols, 2021
Summary: Here, we describe a fractionation protocol optimized to quantify changes in relative abundance of the chromatin-bound proteome (chromatome) by tandem mass tag multiplexing-based tandem mass spectrometry. It has been applied to yeast cells before
Kiran Challa, Jan Seebacher, Susan M. Gasser   +2 more
doaj   +1 more source

An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry [PDF]

, 2010
Background: The goal of this study was to develop and to validate an improved isotope-dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of methylmalonic acid (MMA) in urine.
Michael Vogeser, Lorenzl, Stephan, Stephan Lorenzl, Fabian Kirchhoff, Vogeser, Michael, Kirchhoff, Fabian   +5 more
core   +1 more source

BLINK enables ultrafast tandem mass spectrometry cosine similarity scoring

Scientific Reports, 2023
Metabolomics has a long history of using cosine similarity to match experimental tandem mass spectra to databases for compound identification. Here we introduce the Blur-and-Link (BLINK) approach for scoring cosine similarity.
Thomas V. Harwood, Daniel G. C. Treen, Mingxun Wang, Wibe de Jong, Trent R. Northen, Benjamin P. Bowen   +5 more
doaj   +1 more source

Tandem Native Mass-Spectrometry on Antibody-Drug Conjugates and Submillion da Antibody-Antigen Protein Assemblies on an Orbitrap EMR Equipped with a High-Mass Quadrupole Mass Selector [PDF]

, 2015
Native mass spectrometry is emerging as a powerful tool for the characterization of intact antibodies and antibody-based therapeutics. Here, we demonstrate new possibilities provided by the implementation of a high mass quadrupole mass selector on the ...
Wang, Guanbo, Alexander Makarov (1319898), Heck, Albert J R, Albert J. R. Heck (9680), Andrey Dyachenko (1405822), Ewald T. J. van den Bremer (1583836), Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Guanbo Wang (1329408), Sub Biomol.Mass Spect. and Proteomics, Mike Belov (1583833), Dyachenko, Andrey, Makarov, Alexander, Parren, Paul W H I, Paul W. H. I. Parren (215516), Belov, Mike, De Jong, Rob N., Van Den Bremer, Ewald T J, Rob N. de Jong (843705)   +18 more
core   +2 more sources

Seminolipid and its precursor/degradative product, galactosylalkylacylglycerol, in the testis of saposin A- and prosaposin-deficient mice

Journal of Lipid Research, 2003
Sphingolipid activator proteins (saposins A, B, C, and D) are derived from a common precursor protein (prosaposin) and specifically activate in vivo degradation of glycolipids with short carbohydrate chains.
Keiko Tadano-Aritomi, Junko Matsuda, Hirokazu Fujimoto, Kunihiko Suzuki, Ineo Ishizuka   +4 more
doaj   +1 more source

Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry [PDF]

, 2010
Background: Posaconazole is a novel antifungal drug for oral application intended especially for therapy of invasive mycoses. Due to variable gastrointestinal absorption, adverse side effects, and suspected drug-drug interactions, therapeutic drug ...
Michael Vogeser, Karl J. Lackner, Burghardt, Stephan, Lackner, Karl J., Vogelsberger, Rita, Krueger, Ralf, Stephan Burghardt, Vogeser, Michael, Rita Vogelsberger, Ralf Krüger   +9 more
core   +1 more source