Results 51 to 60 of about 218,280 (260)

Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry

Communications Chemistry, 2021
Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards.
Chia Yen Liew, Chu-Chun Yen, Jien-Lian Chen, Shang-Ting Tsai, Sujeet Pawar, Chung-Yi Wu, Chi-Kung Ni   +6 more
doaj   +1 more source

Electrospray mass spectrometry and tandem mass spectrometry of bimetallic oxovanadium complexes [PDF]

Journal of the American Society for Mass Spectrometry, 2008
A series of six bimetallic oxovanadium complexes (1-6; only one was purified) were investigated by electrospray quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS) in negative-ion mode. Radical molecular anions [M]*(-) were observed in MS mode.
Wu, Zhi-Jun, Xu, Xiao-Ying, Luo, Shi-Wei, Fang, Dong-Mei, Zhang, Guo-Lin   +4 more
openaire   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Determination of Diphenylamine in Gunshot Residue by HPLC-MS/MS

Journal of Forensic Science and Medicine, 2016
A high performance liquid chromatography tandem mass spectrometry/mass spectrometry (HPLC-MS/MS) protocol was developed for the determination of diphenylamine (DPA).
Hongcheng Mei, Yangke Quan, Wenhao Wang, Hong Zhou, Zhanfang Liu, Huixia Shi, Peng Wang   +6 more
doaj   +1 more source

Combined liquid chromatography-tandem mass spectrometry analysis of progesterone metabolites. [PDF]

PLoS ONE, 2015
Progesterone has a number of important functions throughout the human body. While the roles of progesterone are well known, the possible actions and implications of progesterone metabolites in different tissues remain to be determined. There is a growing
Maša Sinreih, Sven Zukunft, Izidor Sosič, Jožko Cesar, Stanislav Gobec, Jerzy Adamski, Tea Lanišnik Rižner   +6 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Determination of 4-Methylimidazole in Ammonia Caramel Using Gas Chromatography–Tandem Mass Spectrometry (GC-MS/MS)

Journal of Food Quality, 2018
One of Maillard reaction products formed in the production of ammonia caramel is 4(5)-methylimidazole (4-MeI) classified as carcinogen. A method of 4-MeI determination based on ion-pair extraction and derivatisation with isobutyl chloroformate with ...
Martyna N. Wieczorek, Krzysztof Przygoński, Henryk H. Jeleń   +2 more
doaj   +1 more source

Elucidation of Nucleic Acid–Drug Interactions by Tandem Mass Spectrometry

CHIMIA, 2014
In continuation of the long tradition of mass spectrometric research at the University of Bern, our group focuses on the characterization of nucleic acids as therapeutic agents and as drug targets.
Yvonne Hari, Adrien Nyakas, Silvan R. Stucki, Stefan Schürch   +3 more
doaj   +1 more source

Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry [PDF]

European Biophysics Journal, 2019
Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR MS can yield accurate elemental compositions of all compounds in a complex sample. Fragmentation caused by ion-neutral, ion-electron, or ion-photon interactions leads to more
Maria A. van Agthoven, Yuko P. Y. Lam, Peter B. O’Connor, Christian Rolando, Marc-André Delsuc   +4 more
openaire   +4 more sources