Results 51 to 60 of about 4,297,069 (302)

Mass spectrometry settings on Agilent 6540 UPLC-tandem-MS system.

, 2018
Mass spectrometry settings on Agilent 6540 UPLC-tandem-MS system.
Lars Löfgren (5896730), Henrik Tjellström (86623), Susanne Pehrsson (5563145), Gunnar Hägglund (62333), Sven Nylander (5563148)   +4 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Tandem Mass Spectrometry across Platforms

Analytical Chemistry
PubChem serves as a comprehensive repository, housing over 100 million unique chemical structures representing the breadth of our chemical knowledge across numerous fields including metabolism, pharmaceuticals, toxicology, cosmetics, agriculture, and many more. Rapid identification of these small molecules increasingly relies on electrospray ionization
Corey Hoang, Winnie Uritboonthai, Linh Hoang, Elizabeth M. Billings, Aries Aisporna, Farshad A. Nia, Rico J. E. Derks, James R. Williamson, Martin Giera, Gary Siuzdak   +9 more
openaire   +3 more sources

Peak intensity prediction in MALDI-TOF mass spectrometry: A machine learning study to support quantitative proteomics [PDF]

, 2008
Timm W, Scherbart A, Boecker S, Kohlbacher O, Nattkemper TW. Peak intensity prediction in MALDI-TOF mass spectrometry: A machine learning study to support quantitative proteomics. BMC Bioinformatics.
Nattkemper, Tim Wilhelm ; https://orcid.org/, Nattkemper Tim W, Wiebke A Timm, Boecker, Sebastian, Kohlbacher, Oliver, Scherbart Alexandra, Kohlbacher Oliver, Sebastian Bocker, Tim W Nattkemper, Alexandra Scherbart, Scherbart, Alexandra, Timm, Wiebke, Timm Wiebke, Oliver Kohlbacher, Böcker Sebastian   +14 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The use of liquid chromatography-tandem mass spectrometry in newborn screening for congenital adrenal hyperplasia: improvements and future perspectives

Frontiers in Endocrinology, 2023
Newborn screening for congenital adrenal hyperplasia using 17-hydroxyprogesterone by immunoassay remains controversial despite screening been available for almost 40 years. Screening is confounded by poor immunoassay specificity, fetal adrenal physiology,
Mark de Hora, Mark de Hora, Natasha Heather, Natasha Heather, Dianne Webster, Dianne Webster, Benjamin Albert, Paul Hofman   +7 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Liquid Chromatography/Electrospray Tandem Mass Spectrometry of methylated purine bases

, 1997
The microheterogeneity of the paracelsin mixture broth of Trichoderma reesei was analysed using mass spectrometric methods, in particular high energy collision-induced dissociation (CID) tandem mass spectrometry (MS/MS). Based on the liquid secondary ion
A. Malorni, G. Randazzo, FERRANTI, PASQUALE, RITIENI, ALBERTO, G. Pocsfalvi, K. Vekey, Dani, Francesca Romana, Decker, R., Moneti, Gloriano, Frosi B., Turillazzi, Stefano, Pieraccini, Giuseppe, Marinello E., Hamdan M., Kühn, G., Holländer, A., PORCELLI, BRUNETTA, Weidner, S., Catinella S., Rovatti L., G Randazzo, A Malorni, G Pocsfalvi, K Vekey, A Ritieni, P Ferranti   +25 more
core   +2 more sources

Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry

Molecules, 2019
Modern mass spectrometry, including electrospray and MALDI, is applied for analysis and structure elucidation of carbohydrates. Cyclic oligosaccharides isolated from different sources (bacteria and plants) have been known for decades and some of them ...
Alexander O. Chizhov, Yury E. Tsvetkov, Nikolay E. Nifantiev   +2 more
doaj   +1 more source

Atomic-level protein structure characterization by tandem-trapped ion mobility spectrometry/tandem-mass spectrometry coupled with UV photodissociation [PDF]

The complexity of the proteome at all levels of protein structure and dynamics renders the systematic identification of how protein modifications alter protein-protein interaction networks and cause disease a formidable, unsolved challenge.
Fanny, Liu, Jusung, Lee, Kaira, Mayberry, Benjamin, Jones, Melvin, Park, Lea, Nienhaus, Alina, Theisen, Erin, Panczyk, Christian, Bleiholder, Christopher, Wootton, Mark, Ridgeway   +10 more
core   +2 more sources