Results 61 to 70 of about 423,639 (301)

Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]

, 2013
The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
Bongiorno, David, Ceraulo, Leopoldo, Drahos, László, Indelicato, Serena, Indelicato, Sergio, Liveri, Vincenzo Turco, Turiák, Lilla, Vékey, Károly   +7 more
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis. [PDF]

, 2015
Data-independent acquisition (DIA) in liquid chromatography (LC) coupled to tandem mass spectrometry (MS/MS) provides comprehensive untargeted acquisition of molecular data.
Arita, Masanori, Cajka, Tomas, Fiehn, Oliver, Higgins, Brendan, Ikeda, Kazutaka, Kanazawa, Mitsuhiro, Kind, Tobias, Ma, Yan, Tsugawa, Hiroshi, VanderGheynst, Jean   +9 more
core  

Mass Spectrometry and Tandem Mass Spectrometry: An Overview

, 2014
In this chapter, a brief overview of fundamentals in mass spectrometry and of its applications in homeland security, forensic sciences and explosive detection, are presented.
openaire   +3 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Current challenges in software solutions for mass spectrometry-based quantitative proteomics [PDF]

, 2012
This work was in part supported by the PRIME-XS project, grant agreement number 262067, funded by the European Union seventh Framework Programme; The Netherlands Proteomics Centre, embedded in The Netherlands Genomics Initiative; The Netherlands ...
A Alexandridou, A Gruhler, A Leitner, A Michalski, A Panchaud, A Thompson, A Wolf-Yadlin, AD Polpitiya, AHP America, AI Nesvizhskii, AI Nesvizhskii, AI Nesvizhskii, AJR Heck, Albert J. R. Heck, AM Mayampurath, B Breukelen van, B Carrillo, B Ma, B Macek, B Schwanhäusser, B Zybailov, BAP Roxas, Bas van Breukelen, BO Keller, C Christin, C Ji, C Kumar, CH Becker, CK Frese, C–C Tsou, D Chelius, D Hoof Van, D MacDougall, D Tsur, D Valkenborg, DH Lundgren, DK Han, DL Swaney, DL Tabb, DL Tabb, DM Good, DN Perkins, E Deutsch, E Qeli, EL Hendrickson, G Audi, GL Finney, H Lam, H Lam, H Liu, H Steen, H Steen, I Beer, IP Shadforth, J Cox, J Cox, J Elias, J Gouw, J Grossmann, J Klimek, J Listgarten, J Meija, J Rappsilber, J Seidler, J Zhang, JC Silva, JF Kellie, JF Timms, JV Olsen, K Flikka, K Kultima, K Podwojski, KA Neilson, KC Hansen, KL Simpson, L Martens, L Ting, LF Waanders, LK Iwai, LN Mueller, M Bantscheff, M Bantscheff, M Bern, M Junqueira, M Kohl, M Mann, M Sandin, M Senko, M Unlü, M Vandenbogaert, MA Baldwin, MA Grobei, MA Kuzyk, MC Codrea, ME Belov, ME Sardiu, MH Elliott, MJ MacCoss, MM Savitski, MW Duncan, N Colaert, N Mischerikow, N Wang, NM Griffin, OA Mirgorodskaya, P Lu, P Mallick, P Mortensen, Pedro R. Cutillas, Peter R. Baker, PJ Boersema, PL Ross, PR Baker, PR Cutillas, PR Cutillas, R Aebersold, R Clarke, R Matthiesen, R Matthiesen, R Purves, R Usaite, R Zhang, RA Bradshaw, RD Smith, RE Moore, RJ Chalkley, RJ Chalkley, RJ Jacob, S Cappadona, S Cappadona, S Carr, S Dasari, S Houel, S Julka, S Ong, S-E Ong, SA Beausoleil, SA Gerber, Salvatore Cappadona, SJ Callister, SK Park, SP Gygi, SY Ow, T Shinkawa, TM Annesley, TS Collier, TT Aye, V Faca, V Lange, VG Tusher, VP Andreev, W Weiss, W Yan, W Zhu, WM Old, WX Schulze, X Yang, Y Ishihama, Y Oda, YJ Kim, Z Khan, Z Khan, Z-Q Ma   +162 more
core   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]

, 2003
In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Schiel, Xaver, Spöhrer, Ute, Vogeser, Michael   +2 more
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Analysis of posttranslational modifications of proteins by tandem mass spectrometry Mass Spectrometry For Proteomics Analysis

BioTechniques, 2006
Protein activity and turnover is tightly and dynamically regulated in living cells. Whereas the three-dimensional protein structure is predominantly determined by the amino acid sequence, posttranslational modification (PTM) of proteins modulates their ...
Martin R. Larsen, Morten B. Trelle, Tine E. Thingholm, Ole N. Jensen   +3 more
doaj   +1 more source