Results 71 to 80 of about 418,182 (306)

An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry [PDF]

, 2010
Background: The goal of this study was to develop and to validate an improved isotope-dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of methylmalonic acid (MMA) in urine.
Bolann BJ, Klee GG, Kushnir MM, Magera M, Rasmussen K   +4 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Mapping Post‐Transcriptional Modifications onto  Transfer Ribonucleic Acid Sequences by Liquid  Chromatography Tandem Mass Spectrometry

Biomolecules, 2017
Liquid chromatography, coupled with tandem mass spectrometry, has become one of the most popular methods for the analysis of post‐transcriptionally modified transfer ribonucleic acids (tRNAs).
Robert L. Ross, Xiaoyu Cao, Patrick A. Limbach   +2 more
doaj   +1 more source

Center-of-Mass iso-Energetic Collision-Induced Decomposition in Tandem Triple Quadrupole Mass Spectrometry

Molecules, 2020
Two scan modes of the triple quadrupole tandem mass spectrometer, namely Collision Induced Dissociation Precursor Ion scan and Neutral Loss scan, allow selectively pinpointing, in a complex mixture, compounds that feature specific chemical groups, which ...
Federico Maria Rubino
doaj   +1 more source

Combined liquid chromatography-tandem mass spectrometry analysis of progesterone metabolites. [PDF]

PLoS ONE, 2015
Progesterone has a number of important functions throughout the human body. While the roles of progesterone are well known, the possible actions and implications of progesterone metabolites in different tissues remain to be determined. There is a growing
Maša Sinreih, Sven Zukunft, Izidor Sosič, Jožko Cesar, Stanislav Gobec, Jerzy Adamski, Tea Lanišnik Rižner   +6 more
doaj   +1 more source

Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]

, 2013
The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
Bongiorno, David, Ceraulo, Leopoldo, Drahos, László, Indelicato, Serena, Indelicato, Sergio, Liveri, Vincenzo Turco, Turiák, Lilla, Vékey, Károly   +7 more
core   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Determination of Diphenylamine in Gunshot Residue by HPLC-MS/MS

Journal of Forensic Science and Medicine, 2016
A high performance liquid chromatography tandem mass spectrometry/mass spectrometry (HPLC-MS/MS) protocol was developed for the determination of diphenylamine (DPA).
Hongcheng Mei, Yangke Quan, Wenhao Wang, Hong Zhou, Zhanfang Liu, Huixia Shi, Peng Wang   +6 more
doaj   +1 more source

41Ca in tooth enamel. part I: A biological signature of neutron exposure in atomic bomb survivors [PDF]

, 2010
The detection of 41Ca atoms in tooth enamel using accelerator mass spectrometry is suggested as a method capable of reconstructing thermal neutron exposures from atomic bomb survivors in Hiroshima and Nagasaki.
A. Arazi, A. Wallner, Arakawa E. T., Auxier J. A., Feldman G. J., Fink D., Fink D., G. Korschinek, G. Rugel, H. J. Maier, Huber T., K. Knie, Knie K., Knie K., Korschinek G., Korschinek G., Kutschera W., Kutschera W., Maier H. J., Marchetti A. A., McAninch J. E., Müller D., N. Nakamura, Nagashima Y., Nakamura N., Nolte E., Paul M., Preston D. L., Preston D. L., Preston D. L., Raisbeck G. M., Romanyukha A. A., Rugel G., Rugel G., Rühm W., Rühm W., Rühm W., Shizuma K., Straume T., Straume T., T. Faestermann, W. Rühm, Wallner A., Wallner A., Wallner A.   +44 more
core   +1 more source

Investigation of Laser Ablation and Brush Pre‐Treatments for AlCu Cold Roll Bonding in Oxygen‐Free Conditions

Advanced Engineering Materials, EarlyView.
It is shown that laser ablation pretreatment under oxygen‐free conditions enables copper–aluminium bonding at significantly lower deformation degrees and improved properties compared to mechanical brushing. Laser ablation further increases interface contact area and induces favourable residual stress states and microstructural compatibility ...
Khemais Barienti, Finn‐Lennard Janthur, Selina Raumel, Sascha Jan Zimmermann, Sarah Seffer, René Gustus, Sebastian Herbst, Marc C. Wurz, Ludger Overmeyer, Wolfgang Maus‐Friedrichs, Hans Jürgen Maier, Florian Nürnberger   +11 more
wiley   +1 more source