Results 71 to 80 of about 1,188,882 (284)
Measurement of kynurenine pathway metabolites by tandem mass spectrometry
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023 Objectives: Recent studies have shown that derangements in kynurenine pathway metabolite levels are associated with various pathologies such as neurodegenerative diseases, schizophrenia, depression, bipolar disorder, rheumatoid arthritis, and cancer ...
Sedat Abusoglu +4 more
doaj
DePS: An improved deep learning model for de novo peptide sequencing [PDF]
arXiv, 2022 De novo peptide sequencing from mass spectrometry data is an important method for protein identification. Recently, various deep learning approaches were applied for de novo peptide sequencing and DeepNovoV2 is one of the represetative models. In this study, we proposed an enhanced model, DePS, which can improve the accuracy of de novo peptide ...
arxiv
MS²PIP: a tool for MS/MS peak intensity prediction [PDF]
, 2013 Motivation: Tandem mass spectrometry provides the means tomatch mass spectrometry signal observations with the chemical entities that generated them. The technology produces signal spectra that contain information about the chemical dissociation pattern ...
Degroeve, Sven, Martens, Lennart
core +2 more sources
Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction [PDF]
, 2002 Quantification of the new immunosuppressant sirolimus (syn. rapamycin; Rapamune((R))) in whole blood by chromatography is essential for its clinical use since no immunoassay is available although monitoring is mandatory.
Fleischer, Claudia +5 more
core +1 more source
Can ion mobility mass spectrometry and density functional theory help elucidate protonation sites in 'small' molecules? [PDF]
, 2013 Ion mobility spectrometry-mass spectrometry (IMS-MS) offers an opportunity to combine measurements and/or calculations of the collision cross-sections and subsequent mass spectra with computational modelling in order to derive the three-dimensional ...
Chowdhry, Babur Z. +4 more
core +1 more source
Crux: Rapid Open Source Protein Tandem Mass Spectrometry Analysis
Journal of Proteome Research, 2014 Efficiently and accurately analyzing big protein tandem mass spectrometry data sets requires robust software that incorporates state-of-the-art computational, machine learning, and statistical methods. The Crux mass spectrometry analysis software toolkit
S. McIlwain +11 more
semanticscholar +1 more source
Biomolecules, 2017 Liquid chromatography, coupled with tandem mass spectrometry, has become one of the most popular methods for the analysis of post‐transcriptionally modified transfer ribonucleic acids (tRNAs).
Robert L. Ross +2 more
doaj +1 more source
Ion Mobility Tandem Mass Spectrometry Enhances Performance of Bottom-up Proteomics
Molecular & Cellular Proteomics, 2014 One of the limiting factors in determining the sensitivity of tandem mass spectrometry using hybrid quadrupole orthogonal acceleration time-of-flight instruments is the duty cycle of the orthogonal ion injection system.
D. Helm +16 more
semanticscholar +1 more source
Communications Chemistry, 2021 Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards.
Chia Yen Liew +6 more
doaj +1 more source
GA-Novo: De Novo Peptide Sequencing via Tandem Mass Spectrometry using Genetic Algorithm [PDF]
arXiv, 2019 Proteomics is the large-scale analysis of the proteins. The common method for identifying proteins and characterising their amino acid sequences is to digest the proteins into peptides, analyse the peptides using mass spectrometry and assign the resulting tandem mass spectra (MS/MS) to peptides using database search tools.
arxiv