Results 81 to 90 of about 286,551 (289)
Elucidation of Nucleic Acid–Drug Interactions by Tandem Mass Spectrometry
CHIMIA, 2014 In continuation of the long tradition of mass spectrometric research at the University of Bern, our group focuses on the characterization of nucleic acids as therapeutic agents and as drug targets.
Yvonne Hari +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A materials and device design concept that comprises a self‐assembled ultra‐thin epitaxial ion‐transporting layer, an amorphous oxide overcoat oxygen‐blocking layer, and a partial filament formed during an electroforming step is proposed for low‐current multilevel resistive switching devices.
Ming Xiao +17 more
wiley +1 more source
Molecules, 2020 Two scan modes of the triple quadrupole tandem mass spectrometer, namely Collision Induced Dissociation Precursor Ion scan and Neutral Loss scan, allow selectively pinpointing, in a complex mixture, compounds that feature specific chemical groups, which ...
Federico Maria Rubino
doaj +1 more source
Advanced Functional Materials, EarlyView.Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan +4 more
wiley +1 more source
RAId DbS: A Mass-Spectrometry Based Peptide Identification Web Server with Knowledge Integration [PDF]
arXiv, 2008 Summary: In anticipation of the individualized proteomics era and the need to integrate knowledge from disease studies, we have augmented our peptide identification software RAId DbS to take into account annotated single amino acid polymorphisms, post-translational modifications, and their documented disease associations while analyzing a tandem mass ...
arxiv
High Mass Accuracy and High Mass Resolving Power FT-ICR Secondary Ion Mass Spectrometry for Biological Tissue Imaging [PDF]
, 2013 Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the sub-micrometer scale.
arxiv +1 more source
Advanced Functional Materials, EarlyView.Using atomic structure and local stability information, recombinant aciniform spider silk proteins are rationally engineered to incorporate a chemically switchable disulfide bond to prevent fiber formation. When disulfide‐locked, these proteins cannot form continuous fibers, whereas the unlocked (reduced) state can.
Anamika Sulekha +7 more
wiley +1 more source
ASS1 gene mutation in a neonate with citrullinemia type Ⅰ [PDF]
Jichu yixue yu linchuang, 2020 Objective To detect blood acylcarnitine and genes in a newborn with suspected citrullinemia, and to detect gene mutations in their parents, so as to clarify their diagnosis and follow-up investigations.
LYU Ya-nan, SONG Dong-po, WANG Wei-qing, CHEN Yan-ping
doaj
Advanced Functional Materials, EarlyView.The non‐fullerene acceptor o‐IDT‐BT‐DCV is used in both binary and ternary blends to investigate the role that it plays in each device architecture. The charge generation pathways are found to differ between the binary and ternary blends with o‐IDT‐BT‐DCV becoming a second donor in the ternary blend.
Hui Jin +10 more
wiley +1 more source
Deep learning for peptide identification from metaproteomics datasets [PDF]
arXiv, 2020 Metaproteomics are becoming widely used in microbiome research for gaining insights into the functional state of the microbial community. Current metaproteomics studies are generally based on high-throughput tandem mass spectrometry (MS/MS) coupled with liquid chromatography.
arxiv