Results 91 to 100 of about 51,416 (309)

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu   +9 more
wiley   +1 more source

Biodegradation and biotransformation of wastewater organics as precursors of disinfection byproducts in water [PDF]

open access: yes, 2010
Laboratory experiments were carried out to investigate wastewater organics as the precursors of disinfection byproducts (DBPs) in drinking water supply.
Li, XY, Liu, JL
core   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu   +15 more
wiley   +1 more source

The effect of a meat extract on iron absorption in young women : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Human Nutrition at Massey University, Palmerston North Campus, New Zealand [PDF]

open access: yes, 2007
Iron deficiency is a global problem for which determinants and solutions need to be investigated. The first part of this study assessed the iron status and dietary intakes of 85 non vegetarian women aged 18-40 years living in the Manawatu region ...
Beck, Kathryn Louise
core  

Effect of phenolic compounds on nematodes- A review [PDF]

open access: yes, 2010
The term, phenolics has been used to describe a group of structurally diverse plant secondary metabolites. This group includes metabolites derived from the condensation of acetate units (terpenoids), those produced by the modification of aromatic amino ...
Ohri, Puja, Pannu, Satinder Kaur
core   +2 more sources

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

open access: yesAdvanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang   +7 more
wiley   +1 more source

Synergistic Effects of Polyphenols and Stannous Ions on Pellicle Modification and Erosion Protection In Situ

open access: yesDentistry Journal
Background: Stannous ions and polyphenols are effective substances in preventive dentistry. The present study’s aim was to investigate whether a combination of these substance groups can achieve increased efficacy.
Jasmin Flemming   +4 more
doaj   +1 more source

Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation

open access: yesAdvanced Science, EarlyView.
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah   +14 more
wiley   +1 more source

Sclerosing Effect of OC-108, a Novel Agent for Hemorrhoids, Is Associated With Granulomatous Inflammation Induced by Aluminum

open access: yesJournal of Pharmacological Sciences, 2005
OC-108 is a novel sclerosing agent for hemorrhoids, containing aluminum potassium sulfate (alum) and tannic acid as its main ingredients. In clinical studies, OC-108 injection therapy for severe internal hemorrhoids proved to be highly effective, not ...
Takashi Ono   +4 more
doaj   +1 more source

Cozymase. A study of purification methods [PDF]

open access: yes, 1927
Cozymase is one of the essential components of the complex enzyme mixture which effects alcoholic fermentation in the absence of living cells. The separation of the mixture into zymase and cozymase was first accomplished by Harden and Young [1] by means ...
Raymond, Albert L.   +1 more
core  

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