Results 111 to 120 of about 11,335 (232)

MAPK3-MYB36-ARF1 module regulates the tanshinone formation in Salvia miltiorrhiza

Plant Signaling & Behavior
Salvia miltiorrhiza, known as Danshen, is a traditional Chinese medicinal plant with significant cardiovascular benefits, attributed to its secondary metabolites, particularly tanshinones.
Yongfeng Xie, Hao Liu
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SmEIL1 transcription factor inhibits tanshinone accumulation in response to ethylene signaling in Salvia miltiorrhiza

Frontiers in Plant Science
Among the bioactive compounds, lipid-soluble tanshinone is present in Salvia miltiorrhiza, a medicinal plant species. While it is known that ethephon has the ability to inhibit the tanshinones biosynthesis in the S.
Xiujuan Li, Man Xu, Ke Zhou, Siyu Hao, Liqin Li, Leran Wang, Wei Zhou, Guoyin Kai   +7 more
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Research Center for Ethnomedicines [PDF]

, 2003
I. 伝統薬物に関するデータベース（ETHMEDmmm）の構築和漢薬・アーユルヴェーダ薬物データベースを新たに開発し，学術データの構築を開始した。Il. 伝統薬物の薬効の評価と解析に関する研究1 ）難治性の神経疾患に対する有効性の検討とそれらの薬理作用の機序に関する研究インド生薬Ash wagandha から，ラット大脳皮質神経の初代培養細胞における神経突起伸展とシナプス形成作用を促進する成分を明らかにし，アルツハイマー病原因物質のアミロイドβ により障害を受けた神経細胞においても ...
Dawa, Meselhy Meselhy Ragab, 小松 かつ子, 東田 千尋, 鄒 坤   +4 more
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Tanshinone IIA effects on ovarian cancer cell line

Journal of Pharmacy and Pharmacology, 2018
Abstract Objectives To explore the potential therapeutic effect of Tanshinone IIA against ovarian cancer in vitro and elucidate the underlying molecular mechanism. Methods The cell survival upon Tanshinone IIA treatment was determined
Nan Li, Liang Yang, Baolian Zhang, Suqin Chen   +3 more
openaire   +2 more sources

Tanshinone ⅡA Enhances Chemosensitivity of Breast Cancer Cells to Doxorubicin and Related Mechanism

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the effects and mechanisms of tanshinone ⅡA on the chemosensitivity of human breast cancer MCF-7 and MDA-MB-231 cells to doxorubicin.
YUAN Yuan, ZHAO Qian, HU Zhansheng
doaj   +1 more source

Tanshinone IIA Selectively Enhances Hyperpolarization-Activated Cyclic Nucleotide–Modulated (HCN) Channel Instantaneous Current

Journal of Pharmacological Sciences, 2009
.: Tanshinone IIA, one of the main active components from the Chinese herb Danshen, is widely used to treat cardiovascular diseases in Asian countries, especially in China.
Qiansheng Liang, Le Yang, Zhaohua Wang, Sufang Huang, Shusheng Li, Guangtian Yang   +5 more
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Synergistic Accumulative Effect of Salicylic Acid and Dibutyl Phthalate on Paclitaxel Production in Corylus avellana Cell Culture [PDF]

, 2013
Suspension cell cultures of Corylus avellana were challenged with salicylic acid and its combined use with dibutyl phthalate solvent. Salicylic acid with concentrations of 12.5, 25 and 50 mg L–1 and 10% (v/v) dibutyl phthalate were used and added on day ...
Behmanesh, M., Ghanati, F., Rezaei, A., Safari, M., Sharafi, Y.   +4 more
core  

Cardiac Potassium Channels: Physiological Insights for Targeted Therapy. [PDF]

, 2017
The development of novel drugs specifically directed at the ion channels underlying particular features of cardiac action potential (AP) initiation, recovery, and refractoriness would contribute to an optimized approach to antiarrhythmic therapy that ...
A. John Camm, Christopher L.-H. Huang, Feng J, Hansen RS, Kamalan Jeevaratnam, Karan R. Chadda, Lepran I, Milnes JT, Nichols CG, Rampe D, Rampe D, Shieh CC, Wang Z, Zhao X, Zhou J   +14 more
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Tanshinone I as a novel therapeutic agent targeting von Willebrand factor-binding protein to mitigate Staphylococcus aureus pathogenicity

Virulence
Staphylococcus aureus (S. aureus) is a prevalent pathogen responsible for a wide range of diseases in humans, contributing to both hospital-acquired and community-acquired infections.
Shiyu Zhou, Haoyan Zou, Yueshan Xu, Dongbin Guo, Zhengjie Su, Li Wang, Bingmei Wang, Yicheng Zhao, Xiangyang Leng, Yanping Wang   +9 more
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Tanshinone IIA Promotes Pulmonary Artery Smooth Muscle Cell Apoptosis in Vitro by Inhibiting the JAK2/STAT3 Signaling Pathway

Cellular Physiology and Biochemistry, 2014
Background: Tanshinone IIA inhibits the proliferation of pulmonary artery smooth muscle cells (PASMCs), but the potential mechanisms of its effects on PASMCs apoptosis remain unclear.
Minggang Chen, Yumei Liu, Dan Yi, Liuping Wei, Yumei Li, Li Zhang   +5 more
doaj   +1 more source