Results 121 to 130 of about 5,178 (152)

Chemical Stability and Bioactivity of tanshinone I, tanshinone IIA, cryptotanshinone and dihydrotanshinone in in vitro test systems

Toxicology Letters, 2023
Danshen Si Wu is a Traditional Chinese Medicine used for menopausal complains. Beside tanshinone IIA (Tan IIA), Danshen also contains tanshinone I (Tan I), cryptotanshinone (CT) and dihydrotanshinone (DT). The aim of this study was to compare the biological activity of these tanshinones and to determine their cytotoxicity and genotoxicity. Purities and
Annika, Roth, Piwen, Zhao, Sebastian T, Soukup, Claudia, Guigas, Joachim, Stärke, Sabine E, Kulling, Patrick, Diel   +6 more
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ChemInform Abstract: TOTALSYNTH. VON TANSHINON‐I, TANSHINON‐II UND CRYPTOTANSHINON

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractDie Diels‐Alder‐Reaktion des Diens (I) mit dem aus 3‐Methyl‐4‐hydroxybenzofuran durch milde Oxidation erhältlichen Chinon (II) liefert nur das Addukt (III), das durch Luftoxidation in Isotanshinon‐II (IV) übergeführt wird.
YOSHINOBU INOUYE, HIROSHI KAKISAWA
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Studies on the spectroscopic behavior of cryptotanshinone, tanshinone IIA, and tanshinone I

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2004
A comparative study on the spectroscopic behavior of cryptotanshinone (CTan), tanshinone IIA (Tan IIA), and tanshinone I (Tan I) has been investigated, including UV-Vis absorption, low temperature phosphorescence (LTP), low temperature fluorescence (LTF), paper substrate-room temperature phosphorescence (PS-RTP), paper substrate-room temperature ...
Jun-Fen, Li, Yu-Xia, Wei, Zhi-Cheng, Xu, Chuan, Dong, Shao-Min, Shuang   +4 more
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Separation of Tanshinone I, Tanshinone IIA, and Cryptotanshinone from Salvia miltiorrhiza Bunge by Normal Phase HPLC

Journal of Liquid Chromatography & Related Technologies, 2009
Abstract A normal phase high performance liquid chromatographic method was established for the simultaneous determination of tanshinones in Salvia miltiorrhiza Bunge. Tanshinones, including cryptotanshinone, tanshinone I, and tanshinone IIA were successfully separated on a silica column using the mixture of n-hexane and dichloromethane (96/4, v/v) as ...
Xiaolong Wan, Ye Wang, Kyung Ho Row
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In VitroCytotoxicity of Tanshinones fromSalvia miltiorrhiza

Planta Medica, 1997
The cytotoxicity-guided fractionation of the roots of Salvia miltiorrhiza B. (Labiatae) extracts led to the isolation of eighteen active principles 1-18, responsible for the cytotoxicity against five cultured human tumor cell lines, i.e., A549 (non-small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCT-15 (colon ...
S Y, Ryu, C O, Lee, S U, Choi
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Tanshinone I inhibits doxorubicin-induced cardiotoxicity by regulating Nrf2 signaling pathway

Phytomedicine, 2022
Doxorubicin (DOX) is a powerful anti-tumor anthracycline drug. However, its clinical use is limited due to the side effect of cardiotoxicity. Tanshinone I (Tan I) is one of the major tanshinones isolated from Salvia miltiorrhiza. Studies have shown that Tan I is effective in the treatment of cardiovascular diseases.
Qianqian Jiang, Xu Chen, Xue Tian, Jingmei Zhang, Siming Xue, Yanyan Jiang, Tiantian Liu, Xiaoping Wang, Qianbin Sun, Yiqin Hong, Chun Li, Dongqing Guo, Yong Wang, Qiyan Wang   +13 more
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Determination of tanshinone I, tanshinone IIA, and cryptotanshinone in Salvia miltiorrhiza bunge and urine sample by HPLC

The Canadian Journal of Chemical Engineering, 2010
AbstractA simple and sensitive HPLC method to detect tanshinone I, tanshinone IIA, and cryptotanshinone in human urine was developed and validated. Chromatographic separation was achieved on a C18 column (4.6 mm × 250 mm, 5 µm) using a mixture of methanol/water (78:22 v/v, containing 0.5% acetic acid) as the mobile phase at a flow rate of 0.5 mL/min ...
Minglei Tian, Kyung Ho Row
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Determination of Cryptotanshinone, Tanshinone I, and Tanshinone IIA inSalvia Miltiorrhizaby Micro HPLC with Amperometric Detection

Analytical Letters, 2013
A highly sensitive and simple method for determining cryptotanshinone (Cry), tanshinone I (Tan I), and tanshinone IIA (Tan IIA) in Salvia miltiorrhiza was developed using micro HPLC with electrochemical detection (µHPLC-ED). The tanshinones were extracted using an ultrasonic method, with methanol as the extractant.
Xianchun Chen, Akira Kotani, Hideki Hakamata, Shouying Du, Jie Wang, Fumiyo Kusu   +5 more
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Tanshinone I: Pharmacological activities, molecular mechanisms against diseases and future perspectives

Phytomedicine, 2023
Tanshinone I (Tan I) is known as one of the important active components in Salvia miltiorrhiza. In recent years, Tan I has received a substantial amount of attention from the research community for various studies being updated and has been shown to possess favorable activities including anti-oxidative stress, regulation of cell autophagy or apoptosis,
Liyuan Ke, Chenhui Zhong, Zhijie Chen, Ziyao Zheng, Shaoguang Li, Bing Chen, Qiaoyi Wu, Hong Yao   +7 more
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Tanshinketolactone, A New Tanshinone from Salvia Miltiorrhiza

Journal of the Chinese Chemical Society, 1996
AbstractA seven‐membered ketolactone, tanshinketolactone (1), was isolated from the root of Salvia miltiorrhiza. Its structure was established by spectroscopic analysis.
Hang‐Ching Lin, Wen‐Liang Chang, Pei‐Lirt Wu, Tian‐Shung Wu   +3 more
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