Results 151 to 160 of about 21,115,427 (202)
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Toxicology Letters, 2023
Danshen Si Wu is a Traditional Chinese Medicine used for menopausal complains. Beside tanshinone IIA (Tan IIA), Danshen also contains tanshinone I (Tan I), cryptotanshinone (CT) and dihydrotanshinone (DT). The aim of this study was to compare the biological activity of these tanshinones and to determine their cytotoxicity and genotoxicity. Purities and
Annika, Roth +6 more
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Danshen Si Wu is a Traditional Chinese Medicine used for menopausal complains. Beside tanshinone IIA (Tan IIA), Danshen also contains tanshinone I (Tan I), cryptotanshinone (CT) and dihydrotanshinone (DT). The aim of this study was to compare the biological activity of these tanshinones and to determine their cytotoxicity and genotoxicity. Purities and
Annika, Roth +6 more
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Studies on the spectroscopic behavior of cryptotanshinone, tanshinone IIA, and tanshinone I
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2004A comparative study on the spectroscopic behavior of cryptotanshinone (CTan), tanshinone IIA (Tan IIA), and tanshinone I (Tan I) has been investigated, including UV-Vis absorption, low temperature phosphorescence (LTP), low temperature fluorescence (LTF), paper substrate-room temperature phosphorescence (PS-RTP), paper substrate-room temperature ...
Chuan Dong, Zhi-Cheng Xu
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Biopharmaceutics & Drug Disposition, 2020
AbstractSalvia miltiorrhiza is one of the most commonly used traditional Chinese medicines in the treatment of cardiovascular and cerebrovascular diseases. Cryptotanshinone (CTS), tanshinone IIA (Tan IIA), dihydrotanshinone I (diTan I), and tanshinone I (Tan I) are the main active compounds in the liposoluble extract of Salvia miltiorrhiza.
Daifei Wang +7 more
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AbstractSalvia miltiorrhiza is one of the most commonly used traditional Chinese medicines in the treatment of cardiovascular and cerebrovascular diseases. Cryptotanshinone (CTS), tanshinone IIA (Tan IIA), dihydrotanshinone I (diTan I), and tanshinone I (Tan I) are the main active compounds in the liposoluble extract of Salvia miltiorrhiza.
Daifei Wang +7 more
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Total Synthesis of Tanshinone I
Journal of Natural Products, 2017A novel total synthesis of tanshinone I (1) via the intermediate 3-hydroxy-8-methyl-1,4-phenanthrenedione (8) is described. The low overall yields and the use of expensive reagents in the synthesis process were minimized by the use of the Diels-Alder reaction to directly construct the 1,4-phenanthrenedione scaffold, providing tanshinone I (1) in only ...
Nan Wu +4 more
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The Canadian Journal of Chemical Engineering, 2010
AbstractA simple and sensitive HPLC method to detect tanshinone I, tanshinone IIA, and cryptotanshinone in human urine was developed and validated. Chromatographic separation was achieved on a C18 column (4.6 mm × 250 mm, 5 µm) using a mixture of methanol/water (78:22 v/v, containing 0.5% acetic acid) as the mobile phase at a flow rate of 0.5 mL/min ...
Minglei Tian, Kyung Ho Row
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AbstractA simple and sensitive HPLC method to detect tanshinone I, tanshinone IIA, and cryptotanshinone in human urine was developed and validated. Chromatographic separation was achieved on a C18 column (4.6 mm × 250 mm, 5 µm) using a mixture of methanol/water (78:22 v/v, containing 0.5% acetic acid) as the mobile phase at a flow rate of 0.5 mL/min ...
Minglei Tian, Kyung Ho Row
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Analytical Letters, 2013
A highly sensitive and simple method for determining cryptotanshinone (Cry), tanshinone I (Tan I), and tanshinone IIA (Tan IIA) in Salvia miltiorrhiza was developed using micro HPLC with electrochemical detection (µHPLC-ED). The tanshinones were extracted using an ultrasonic method, with methanol as the extractant.
Xianchun Chen +5 more
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A highly sensitive and simple method for determining cryptotanshinone (Cry), tanshinone I (Tan I), and tanshinone IIA (Tan IIA) in Salvia miltiorrhiza was developed using micro HPLC with electrochemical detection (µHPLC-ED). The tanshinones were extracted using an ultrasonic method, with methanol as the extractant.
Xianchun Chen +5 more
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ChemInform Abstract: TOTALSYNTH. VON TANSHINON‐I, TANSHINON‐II UND CRYPTOTANSHINON
Chemischer Informationsdienst. Organische Chemie, 1970AbstractDie Diels‐Alder‐Reaktion des Diens (I) mit dem aus 3‐Methyl‐4‐hydroxybenzofuran durch milde Oxidation erhältlichen Chinon (II) liefert nur das Addukt (III), das durch Luftoxidation in Isotanshinon‐II (IV) übergeführt wird.
YOSHINOBU INOUYE, HIROSHI KAKISAWA
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In VitroCytotoxicity of Tanshinones fromSalvia miltiorrhiza
Planta Medica, 1997The cytotoxicity-guided fractionation of the roots of Salvia miltiorrhiza B. (Labiatae) extracts led to the isolation of eighteen active principles 1-18, responsible for the cytotoxicity against five cultured human tumor cell lines, i.e., A549 (non-small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCT-15 (colon ...
S Y, Ryu, C O, Lee, S U, Choi
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Journal of Liquid Chromatography & Related Technologies, 2009
Abstract A normal phase high performance liquid chromatographic method was established for the simultaneous determination of tanshinones in Salvia miltiorrhiza Bunge. Tanshinones, including cryptotanshinone, tanshinone I, and tanshinone IIA were successfully separated on a silica column using the mixture of n-hexane and dichloromethane (96/4, v/v) as ...
Xiaolong Wan, Ye Wang, Kyung Ho Row
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Abstract A normal phase high performance liquid chromatographic method was established for the simultaneous determination of tanshinones in Salvia miltiorrhiza Bunge. Tanshinones, including cryptotanshinone, tanshinone I, and tanshinone IIA were successfully separated on a silica column using the mixture of n-hexane and dichloromethane (96/4, v/v) as ...
Xiaolong Wan, Ye Wang, Kyung Ho Row
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