Results 161 to 170 of about 21,115,427 (202)

Tanshinone IIA and tanshinone I production by Trichoderma atroviride D16, an endophytic fungus in Salvia miltiorrhiza

Phytomedicine, 2012
In this study the isolation of an endophytic fungus from the root of the medicinal herb Salvia miltiorrhiza Bunge is reported for the first time. The fungus produced tanshinone I and tanshinone IIA in rich mycological medium (potato dextrose broth) under shake flask and bench scale fermentation conditions.
Qianliang, Ming, Ting, Han, Wenchao, Li, Qiaoyan, Zhang, Hong, Zhang, Chengjian, Zheng, Fang, Huang, Khalid, Rahman, Luping, Qin   +8 more
openaire   +2 more sources

A facile three-step total synthesis of tanshinone I

Journal of Asian Natural Products Research, 2016
A facile synthetic approach for total synthesis of tanshinone I has been accomplished. The key precursor is a novel compound, epoxy phenanthraquinone. And this synthesis of tanshinone I is achieved in only three simple stages, which include Diels-Alder reaction, Δ(2)-Weitz-Scheffer-type epoxidation, and Feist-Bénary reaction from commercially available
Han-Rui, Yang, Jie-Jie, Wang, Peng-Peng, Shao, Si-Yi, Yuan, Xu-Qin, Li   +4 more
openaire   +2 more sources

Enhancement of solubility and dissolution rate of cryptotanshinone, tanshinone I and tanshinone IIA extracted from Salvia miltiorrhiza

Archives of Pharmacal Research, 2012
Cryptotanshinone, tanshinone I and tanshinone IIA are three major components in the extract of Salvia miltiorrhiza with pharmacological significance. However, their effective utilization is limited due to poor water solubility and bioavailability.
Hang, Yu, Robhash Kusam, Subedi, Pushp R, Nepal, Yoon G, Kim, Hoo-Kyun, Choi   +4 more
openaire   +2 more sources

The Correlation ofSalvia miltiorrhizaExtract–Induced Regulation of Osteoclastogenesis with the Amount of Components Tanshinone I, Tanshinone IIA, Cryptotanshinone, and Dihydrotanshinone

Immunopharmacology and Immunotoxicology, 2008
Tanshinone I, tanshinone IIA, cryptotanshinone, and dihydrotanshinone are compounds that have been isolated from the root of Salvia miltiorrhiza (SM), which is also known as "Danshen." The SM extract has been used successfully in China for treating postmenopausal syndrome.
Hae-Kyung, Kim, Eun-Rhan, Woo, Hae-Won, Lee, Hyung-Rae, Park, Hyun-Nam, Kim, Yeon-Kwan, Jung, Je-Yong, Choi, Soo-Wan, Chae, Hyung-Ryong, Kim, Han-Jung, Chae   +9 more
openaire   +2 more sources

Simultaneous determination of cryptotanshinone, tanshinone I and tanshinone IIA in traditional Chinese medicinal preparations containing Radix salvia miltiorrhiza by HPLC

Journal of Pharmaceutical and Biomedical Analysis, 2005
A reversed-phase high performance liquid chromatographic method was established for the simultaneous determination of tanshinones in five kinds of traditional Chinese medicinal preparations (TCMPs) containing Radix salvia miltiorrhiza (Chinese herbal name: Danshen).
Meiping Zhao, Wenbao Chang
exaly   +3 more sources

Tanshinketolactone, A New Tanshinone from Salvia Miltiorrhiza

Journal of the Chinese Chemical Society, 1996
AbstractA seven‐membered ketolactone, tanshinketolactone (1), was isolated from the root of Salvia miltiorrhiza. Its structure was established by spectroscopic analysis.
Hang‐Ching Lin, Wen‐Liang Chang, Pei‐Lirt Wu, Tian‐Shung Wu   +3 more
openaire   +1 more source

Effect and Mechanism of Tanshinone I on the Radiosensitivity of Lung Cancer Cells

Molecular Pharmaceutics, 2018
Resistance to radiotherapy is one of the main obstacles to improving cancer prognoses. To effectively destroy cancer cells, novel radiation sensitizers are needed. Recently, several natural products have been shown to exhibit promising tumor-killing properties.
Yuanliang Yan, Weiping Su, Shuangshuang Zeng, Long Qian, Xi Chen, Jie Wei, Na Chen, Zhicheng Gong, Zhijie Xu   +8 more
openaire   +2 more sources

Combination of Microwave Assisted Micellar Extraction and Liquid Chromatography for Determination of Cryptotanshinone, Tanshinone I, and Tanshinone IIA in Salvia Miltiorrhiza Bunge

Journal of Liquid Chromatography & Related Technologies, 2009
Abstract A new method based on the microwave assisted micellar extraction technique (MAME) has been optimized for the extraction of tanshinones from the traditional Chinese medicine-Salvia miltiorrhiza Bunge. Non-ionic surfactant Genapol X-080 solution was employed as extractant.
Zhihong Shi, Yu Wang, Hongyi Zhang
openaire   +1 more source

Tanshinone I inhibits doxorubicin-induced cardiotoxicity by regulating Nrf2 signaling pathway

Phytomedicine, 2022
Doxorubicin (DOX) is a powerful anti-tumor anthracycline drug. However, its clinical use is limited due to the side effect of cardiotoxicity. Tanshinone I (Tan I) is one of the major tanshinones isolated from Salvia miltiorrhiza. Studies have shown that Tan I is effective in the treatment of cardiovascular diseases.
Qianqian Jiang, Xu Chen, Xue Tian, Jingmei Zhang, Siming Xue, Yanyan Jiang, Tiantian Liu, Xiaoping Wang, Qianbin Sun, Yiqin Hong, Chun Li, Dongqing Guo, Yong Wang, Qiyan Wang   +13 more
openaire   +2 more sources

[Absorption mechanism of tanshinone II A, cryptotanshinone, tanshinone I and tanshinones extract in rat small intestine in vivo].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011
To study the absorption mechanism of tanshinones in the roots of Salvia miltiorrhiza as well as the interaction between the components in the effective fraction.The model of intestinal absorption in vivo was used and the concentrations of the tanshinones were determined by HPLC, the apparent absorption constant (K(a)) and half life of absorption (t1/2)
Hongbo, Yan, Qing, Wu, Shouying, Du, Yinhua, Yang, Lin, Zhou, Xuemin, Li   +5 more
openaire   +1 more source