Results 141 to 150 of about 79,005 (262)
Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases
Drug Design, Development and Therapy, 2020 Salvia miltiorrhiza: (Danshen) is a significant (traditional Chinese medication) natural remedy, enhancing blood circulation and clear blood stasis.
Rui Guo +6 more
semanticscholar +1 more source
Plant Biotechnology Journal, Volume 24, Issue 2, Page 384-401, February 2026.ABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Renjun Qu +9 more
wiley +1 more source
Tanshinone IIA protects against pulmonary arterial hypertension in broilers
Poultry Science, 2017 This investigation was conducted to study the effects of tanshinone IIA (TIIA) on pulmonary arterial hypertension (PAH) in broilers. Two-hundred newly hatched Arbor Acre commercial broilers were randomly divided into 3 groups. All groups, with the exception of the control group (tap water), were given NaCl water (0.3%) starting on the d 15, and ...
Guoliang, Hu +10 more
openaire +2 more sources
Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.ABSTRACT Background Spinal cord injury (SCI) leads to severe neurological dysfunction. Current therapeutic strategies remain limited, with poor recovery rates. Oxidative stress and ferroptosis are key mechanisms underlying secondary SCI. Paeoniflorin has anti‐inflammatory, antioxidant, and neuroprotective properties; however, its role in regulating ...
Zongyu Zhang +3 more
wiley +1 more source
Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation
Synthetic and Systems Biotechnology, 2016 Two potent anti-MRSA tanshinone glycosides (1 and 2) were discovered by targeted microbial biotransformation, along with rapid identification via MS/MS networking.
Wenni He +15 more
doaj +1 more source
Sodium tanshinone IIA sulfonate stimulated Cl− secretion in mouse trachea
PLOS ONE, 2017 Sodium tanshinone IIA sulfonate (STS) is a derivate of tanshinone IIA, a lipophilic compound in Salvia miltiorrhiza. This study aimed to investigate the effect of STS on ion transport in mouse tracheal epithelium and the mechanisms underlying it. Short-circuit current (Isc) was measured to evaluate the effect of STS on transepithelial ion transport ...
Peng-Xiao Chen +6 more
openaire +4 more sources
Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]
, 2009 © 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Abbey +112 more
core +2 more sources
Frontiers in Pharmacology, 2019 Bioactive chemical constitutes from the root of Salvia miltiorrhiza classified in two major groups, viz., liposoluble tanshinones and water-soluble phenolics. Tanshinone IIA is a major lipid-soluble compound having promising health benefits.
Jie Ren +5 more
doaj +1 more source
Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 [PDF]
, 2018 Sphingosine kinase 1 (SphK1) upregulation is associated with pathologic pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), but the mechanisms controlling its expression are undefined.
Chen, Jiwang +6 more
core +1 more source
Cellular Physiology and Biochemistry, 2015 Aims: Estrogen plays a protective role in atherosclerosis. Our preliminary work demonstrated that the active conformation of Tanshinone IIA(TanIIA) is similar to the 17ß-estradiol and it can bind to the estrogen receptor.
Xin Liu +7 more
doaj +1 more source