A review study on medicinal plants affecting amnesia through cholinergic system [PDF]
Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar. +3 more
core
Cardiac Potassium Channels: Physiological Insights for Targeted Therapy. [PDF]
The development of novel drugs specifically directed at the ion channels underlying particular features of cardiac action potential (AP) initiation, recovery, and refractoriness would contribute to an optimized approach to antiarrhythmic therapy that ...
A. John Camm +14 more
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Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu +7 more
wiley +1 more source
Inhibition of tanshinone IIA on renin activity protected against osteoporosis in diabetic mice
Context Salvia miltiorrhiza Bge. (Labiatae) (SMB) is applied clinically for management of diabetic osteoporosis in China, and research results has suggested its potential action on renin–angiotensin system (RAS). Objective This study screens and explores
Jingjing Zhang +4 more
doaj +1 more source
Salvia mltiorrhiza Bunge (SMB) is native to China, whose dried root has been used as medicine. A few chromatographic- or spectrometric-based methods have already been used to analyze the lipid-soluble components in SMB.
Yuanyuan Li +7 more
doaj +1 more source
Breathing Signature as Vitality Score Index Created by Exercises of Qigong: Implications of Artificial Intelligence Tools Used in Traditional Chinese Medicine. [PDF]
Rising concerns about the short- and long-term detrimental consequences of administration of conventional pharmacopeia are fueling the search for alternative, complementary, personalized, and comprehensive approaches to human healthcare.
Dethlefs, Brent A +6 more
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Adjunctive Therapies in Periodontitis: Current Concepts and the Future
This graphical abstract summarizes the translational pathway from preclinical research to clinical implementation of adjunctive therapies for periodontitis, highlighting key barriers, innovative therapeutic strategies, and emerging tools that aim to bridge experimental discoveries with patient care.
Rafael Scaf de Molon +4 more
wiley +1 more source
Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis in rats
Idiopathic pulmonary fibrosis is a chronic and progressive fibrotic lung disorder with unknown etiology and a high mortality rate. Tanshinone ⅡA (Tan ⅡA) is a lipophilic diterpene extracted from the Chinese herb Salvia miltiorrhiza Bunge with diverse biological functions.
HE, HUANYU +6 more
openaire +3 more sources
Research Center for Ethnomedicines [PDF]
I. 伝統薬物に関するデータベース(ETHMEDmmm)の構築和漢薬・アーユルヴェーダ薬物データベースを新たに開発し,学術データの構築を開始した。Il. 伝統薬物の薬効の評価と解析に関する研究1 )難治性の神経疾患に対する有効性の検討とそれらの薬理作用の機序に関する研究インド生薬Ash wagandha から,ラット大脳皮質神経の初代培養細胞における神経突起伸展とシナプス形成作用を促進する成分を明らかにし,アルツハイマー病原因物質のアミロイドβ により障害を受けた神経細胞においても ...
Dawa +4 more
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Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc [PDF]
Background Oridonin, a tetracycline diterpenoid compound, has the potential antitumor activities. Here, we evaluate the antitumor activity and action mechanisms of oridonin in colorectal cancer.
Feng-Hou Gao +13 more
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