Results 121 to 130 of about 79,005 (262)
Pharmaceutical Biology, 2018 Context: Tanshinone IIA, commercially produced from Salvia miltiorrhiza Bunge (C.Y.Wu) (Labiatae), has various biological benefits. Currently, this compound is mainly extracted from plants.
Pengyu Zhang +5 more
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Journal of International Medical Research, 2020 Objective To investigate the effects of tanshinone IIA on the transforming growth factor-β1 (TGF-β1)/Smads signaling pathway in angiotensin II-treated hepatic stellate cells (HSCs).
Guo-wei Wei +3 more
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Therapeutic Angiogenesis of Chinese Herbal Medicines in Ischemic Heart Disease:A Review [PDF]
, 2018 Ischemic heart disease (IHD) is one of the primary causes of death around the world. Therapeutic angiogenesis is a promising innovative approach for treating IHD, improving cardiac function by promoting blood perfusion to the ischemic myocardium.
Chen, Xing +7 more
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Food Science &Nutrition, Volume 14, Issue 2, February 2026.Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés +13 more
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Atlas‐Based Mapping of Traditional Chinese Medicine Effects on Tumor Microcirculation Regulation
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.ABSTRACT Background Tumor microcirculation plays a central role in the onset and progression of hypoxia, therapeutic resistance, and immune evasion within the tumor microenvironment. Traditional Chinese Medicine (TCM), characterized by its multi‐targeted and systemic regulatory properties, has garnered increasing attention for its potential to modulate
I Ho +3 more
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Tanshinone IIA Interacts with DNA by Minor Groove-Binding
Biological and Pharmaceutical Bulletin, 2008 Tanshen has long been widely used as a traditional Chinese medicine. Tanshinone IIA (Tan IIA) is the most abundant lipophilic constituent of Tanshen which has antitumor activity but the mechanism is poorly understood. Some preliminary reports hypothesized that it is a DNA intercalator and that the furano-o-quinone moiety could produce free radicals ...
Zhichao, Zhang +5 more
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Ferric Citrate Attenuates Cardiac Hypertrophy and Fibrosis in a Rat Model of Chronic Kidney Disease. [PDF]
, 2019 IntroductionChronic kidney disease (CKD) promotes hypertrophy and fibrosis in heart, and increases the risk of cardiovascular mortality. Ferric citrate is a dietary phosphate binder used to control hyperphosphatemia in CKD patients.
Goto, Masaki +6 more
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Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing
Plant Biotechnology Journal, Volume 24, Issue 5, Page 2858-2860, May 2026.
Haomiao Yu +9 more
wiley +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
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NGHIÊN CỨU PHƯƠNG PHÁP PHÂN LẬP TANSHINONE IIA TỪ ĐAN SÂM LÀM CHẤT ĐỐI CHIẾU
Tạp chí Khoa học Đại học Đà Lạt, 2015 Tanshinone IIA đã được phân lập từ đan sâm (Salvia mitiorrhiza) làm chất đối chiếu. Phương pháp phân lập gồm các bước: chiết các thành phần thân dầu từ rễ đan sâm bằng n-hexan, phân lập tanshinone IIA bằng sắc ký cột silicagel và tinh chế bằng phương ...
Trịnh Thị Điệp, Trần Thanh Hà
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