Results 101 to 110 of about 79,005 (262)

Tanshinone IIA inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway

Bangladesh Journal of Pharmacology, 2015
In human cervical cancer cells pro-apoptotic effect of tanshinone IIA isolated from the ethanol extract of Scutellaria barbata was investigated. Tanshinone IIA treatment resulted in apoptosis and mitochondrial membrane potential loss in the cervical ...
Hu Li, Yan Xu, Li Yang, Lei He
doaj  

Influence of Tanshinone IIA on the Apoptosis of Human Esophageal Ec-109 Cells

Natural Product Communications, 2016
The induced-apoptosis effect and mechanism of human esophageal cancer Ec-109 cells via tanshinone IIA was investigated. The Ec-109 cells were cultured in vitro with different concentrations of tanshinone IIA (2 μg/mL, 4 μg/mL, or 8 μg/mL) for 12, 24, 36,
Yan-Qin Zhu, Bai-Yan Wang, Fang Wu, Yong-Kang An, Xin-Qiang Zhou   +4 more
doaj   +1 more source

The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line

Acta Pharmaceutica Sinica B, 2015
The effects of tanshinone IIA on the proliferation of the human non-small cell lung cancer cell line A549 and its possible mechanism on the VEGF/VEGFR signal pathway were investigated.
Jun Xie, Jiahui Liu, Heng Liu, Shihui Liang, Meigui Lin, Yueyu Gu, Taoli Liu, Dongmei Wang, Hui Ge, Sui-lin Mo   +9 more
doaj   +1 more source

Tanshinone IIA attenuates nerve structural and functional damage induced by nerve crush injury in rats. [PDF]

PLoS ONE, 2018
After peripheral nerve crush injury, the fibers of distal nerve segments gradually disintegrate, and axons regrow from the proximal nerve segment, eventually reaching the target organ.
Zhiyong Wang, Xiaomei Yang, Weiguang Zhang, Peixun Zhang, Baoguo Jiang   +4 more
doaj   +1 more source

A Friendly Relationship between Endophytic Fungi and Medicinal Plants: A Systematic Review [PDF]

, 2016
Endophytic fungi or endophytes exist widely inside the healthy tissues of living plants, and are important components of plant micro-ecosystems. Over the long period of evolution, some co-existing endophytes and their host plants have established a ...
Abd_Allah, Ahmad, Amna, Bacon, Barazani, Bashyal, Behie, Bittleston, Bussaban, Camatti-Sartori, Cao, Cao, Carroll, Cavaglieri, Chakravarthi, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chithra, Chutima, Cui, D'Amico, Dai, Deng, Dingle, Duan, Eyberger, Faeth, Fan, Firáková, Gangadevi, Gangadevi, Gange, Gao, Gunatilaka, Guo, Guo, Guo, Gómez-Vidal, Harper, Hartley, Herrera-Carrillo, Huang, Huang, Jiang, Ju, Khan, Kim, Kour, Kozyrovska, Kumaran, Kumaran, Kusari, Kusari, Kusari, Kusari, Kusari, Kusari, Li, Li, Li, Li, Li, Li, Liu, Liu, Lu, Maciá-Vicente, Maehara, Meng, Ming, Mo, Moricca, Nascimento, Nejad, Osono, Pan, Puri, Puri, Qiu, Qiu, Redman, Rehman, Ren, Richardson, Rodrigues, Rodriguez, Rodriguez, Saikkonen, Saikkonen, Senthil Kumaran, Sherameti, Shrestha, Shwab, Shweta, Sieber, Silva, Song, Stierle, Stierle, Strobel, Strobel, Strobel, Sumarah, Sun, Sun, Suryanarayanan, Tan, Tang, Tofern, Torres, Unterseher, Venkatachalam, Wang, Wang, Wang, Wang, Wang, Wang, Waqas, Weyens, Wu, Yan, Yang, Yang, Yin, Yu, Zeng, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhou, Zhou   +141 more
core   +1 more source

Anti-SARS-CoV-2 activities of tanshinone IIA, carnosic acid, rosmarinic acid, salvianolic acid, baicalein, and glycyrrhetinic acid between computational and in vitro insights

RSC Advances, 2021
Six compounds namely, tanshinone IIA (1), carnosic acid (2), rosmarinic acid (3), salvianolic acid B (4), baicalein (5), and glycyrrhetinic acid (6) were screened for their anti-SARS-CoV-2 activities against both the spike (S) and main protease (Mpro ...
Dalia Elebeedy, W. Elkhatib, A. Kandeil, Aml Ghanem, Omnia Kutkat, Radwan Alnajjar, M. Saleh, Ahmed I. Abd El Maksoud, Ingy Badawy, A. Al-karmalawy   +9 more
semanticscholar   +1 more source

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu, Jia Song Deon Chon, Yuxiao Feng, Kang Liang, Shiming Li, Can Yang Zhang, Jun Ge   +6 more
wiley   +1 more source

Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study [PDF]

Evidence-Based Complementary and Alternative Medicine, 2011
Tanshinone IIA (Tan IIA) and sodium tanshinone IIA sulfonate (STS) were found to have protective effects on cardiomyocyte against adriamycin‐induced damage and may be used clinically. It is unclear whether the supplementation of STS or Tan IIA would affect the anticancer activity of anthracycline.
Chan, Szu-Erh, Lai, Hung-Wen, Su, Chin-Cheng, Kuo, Shou-Jen, Chien, Su-Yu, Lin, Hui-Yi, Chen, Dar-Ren   +6 more
openaire   +2 more sources

Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol‐Induced Ischemic Myocardial Infarction via TLR4/NF‐κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
ZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Jiawen Huang, Tian Yu, Guoyi Li, Kechao Nie, Donghua Liu, Cong Meng, Xiaoling Shen, Linchun Fu, Liang Long, Zhuotao Fu, Zhitong Deng, Yingjie Hu   +11 more
wiley   +1 more source

Biological aspects of mTOR in leukemia [PDF]

, 2018
The mammalian target of rapamycin (mTOR) is a central processor of intra-and extracellular signals, regulating many fundamental cellular processes such as metabolism, growth, proliferation, and survival.
Bianchi, Mp, Gianfelici, V, Mirabilii, S, Piedimonte, M, Ricciardi, Mr, Tafuri, A.   +5 more
core   +1 more source