Results 51 to 60 of about 735,136 (286)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Adiabatically-tapered fiber mode multiplexers

Optics Express, 2014
Simple all-fiber three-mode multiplexers were made by adiabatically merging three dissimilar single-mode cores into one multimode core. This was achieved by collapsing air holes in a photonic crystal fiber and (in a separate device) by fusing and tapering separate telecom fibers in a fluorine-doped silica capillary.
S. Yerolatsitis, I. Gris-Sánchez, T. A. Birks   +2 more
openaire   +2 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

The Structure and Applications of Fused Tapered Fiber Optic Sensing: A Review

Photonics
Tapered optical fibers have continuously evolved in areas such as distributed sensing and laser generation in recent years. Their high sensitivity, ease of integration, and real-time monitoring capabilities have positioned them as a focal point in ...
Siqi Ban, Yudong Lian
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Sensing Performance of Modified Single Mode Optical Fiber Coated With Nanomaterials-Based Ammonia Sensors Operated in the C-Band

IEEE Access, 2019
An etched tapered single mode optical fiber (SMF) coated with polyaniline (PANI) nanofibers is developed to detect ammonia (NH3) in low concentrations. The SMF is etched with hydrofluoric acid and subsequently tapered using a glass processing workstation.
Husam Abduldaem Mohammed, Norizah Abdul Rahman, Muhammad Zamharir Ahmad, Muhammad Hafiz Abu Bakar, Siti Barirah Ahmad Anas, Mohd Adzir Mahdi, Mohd Hanif Yaacob   +6 more
doaj   +1 more source

The use of a fiber comb filter fabricated by a CO2 laser irradiation to improve the resolution of a ratiometric wavelength measurement system [PDF]

, 2012
An edge filter based ratiometric wavelength measurement system is modelled and analysed in this paper. The results confirm that the noise of input signal and photodetectors limit the resolution of the wavelength measurement system.
Brambilla, Gilberto, Ding, Ming, Gerald Farrell, Yuliya Semenova, Gilberto Brambilla, Farrell, Gerald, Semenova, Yuliya, Pengfei Wang, Ming Ding, Qiang Wu, Wang, Pengfei, Wu, Qiang   +11 more
core   +1 more source

High energy mode-locked Yb-doped fiber laser with Bi2Te3 deposited on tapered-fiber

, 2017
The report presents the high energy mode-locking operation in an all-normal-dispersion Yb-doped mode-locked fiber laser based on evanescent field interaction with tapered fiber deposited with Bi2Te3 topological insulator.
Li, Lu (liluyoudian@163.com), Lu Li, Wang, Yonggang, Sun, Hang, Lin, Tao, Li, Lu, Yonggang Wang, Tao Lin, Wang, Xi, Xi Wang, Hang Sun   +10 more
core   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source