Results 181 to 190 of about 121,418 (252)

Physiologically Based Pharmacokinetic Modeling to Characterize the Disposition of Topiramate in Children with and without Obesity

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.
Abstract Topiramate (TPM) is used to treat seizures in adults and children ≥2 years. In children, TPM dosing is body weight based. It is unknown whether children with obesity may benefit from an alternative dosing strategy. We developed a novel physiologically based pharmacokinetic (PBPK) model for TPM that accounts for age‐ and obesity‐related changes
Patricia D. Maglalang   +14 more
wiley   +1 more source

Correction: CPX-351 vs. conventional chemotherapy cardiotoxicity in high-risk AML: a post hoc phase III trial analysis. [PDF]

open access: yesCardiooncology
Mitchell JD   +12 more
europepmc   +1 more source

A novel approach to estimate non‐algal particle absorption for improved retrieval of pigment concentrations in coastal waters

open access: yesLimnology and Oceanography: Methods, Volume 24, Issue 10, October 2026.
Abstract Phytoplankton play a central role in ocean biogeochemistry and understanding their composition and variability is critical for monitoring marine ecosystem dynamics. Continuous spectrophotometric measurements (using a Seabird Sci. AC‐S) along ship tracks enable high‐resolution measurements of particle spectral absorption (apλ), and beam ...
Margherita Costanzo   +4 more
wiley   +1 more source

Epigenomic profiling links IGF2 overexpression to anthracycline resistance in colorectal cancer organoids. [PDF]

open access: yesJCI Insight
Hogenson TL   +14 more
europepmc   +1 more source

Growth and human milk intake outcomes from postdischarge feedings among very‐low‐birth‐weight preterm infants: A systematic review

open access: yesNutrition in Clinical Practice, Volume 41, Issue 5, Page 1334-1348, October 2026.
Abstract Background Preterm infants of <34 weeks gestation or <1500 g are at risk for postnatal growth failure and often require nutrition support after discharge. Despite expert recommendations for postdischarge human milk (HM) fortification or nutrient‐enriched formula feeding, the effects of current feeding strategies on growth and HM intake remain ...
Tara Rebele   +5 more
wiley   +1 more source

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