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Science-Based Targets: On Target? [PDF]

open access: yesSustainability, 2021
Companies are increasingly seeking to align their actions with the goals of the Paris Agreement. Over 1000 such companies have committed to the science-based targets initiative which seeks to align corporate carbon reduction targets with global decarbonisation trajectories. These ‘science-based targets’ are developed using a common set of resources and
Giesekam, J   +3 more
openaire   +6 more sources

Targeting Target Shareholders [PDF]

open access: yesSSRN Electronic Journal, 2014
We integrate heterogeneity and uncertainty in investor valuations into a model of takeovers. Investors have dispersed valuations, holding shares in firms they value more highly, and a successful offer must win approval from the median target shareholder.
Dan Bernhardt   +2 more
openaire   +5 more sources

To Target or Not to Target, That Is the Question [PDF]

open access: yesJournal of Clinical Oncology, 2013
esting results achieved with dacomitinib (PF-00299804), a pan– human epidermal growth factor receptor (HER) inhibitor. The authors demonstrated that dacomitinib was able to selectively, irreversibly (covalently) bind to the adenosine triphosphate domain of each of the three kinase-active members of the HER family: epidermal growth factor receptor (EGFR)
M. C. Garassino   +4 more
openaire   +3 more sources

Cooperative Search Optimization of an Unknown Dynamic Target Based on the Modified TPM

open access: yesInternational Journal of Aerospace Engineering, 2022
Aiming to address the problem of unknown dynamic target trajectory prediction and search path optimization in unmanned aerial vehicle (UAV) swarm path planning, this paper proposes a target search algorithm based on a modified target probability map (TPM)
Kaixin Cheng   +4 more
doaj   +1 more source

Few Samples of SAR Automatic Target Recognition Based on Enhanced-Shape CNN

open access: yesJournal of Mathematics, 2021
Synthetic Aperture Radar (SAR), as one of the important and significant methods for obtaining target characteristics in the field of remote sensing, has been applied to many fields including intelligence search, topographic surveying, mapping, and ...
Mengmeng Huang, Fang Liu, Xianfa Meng
doaj   +1 more source

MicroRNAs – targeting and target prediction [PDF]

open access: yesNew Biotechnology, 2010
MicroRNAs (miRNAs) are a class of small noncoding RNAs that can regulate many genes by base pairing to sites in mRNAs. The functionality of miRNAs overlaps that of short interfering RNAs (siRNAs), and many features of miRNA targeting have been revealed experimentally by studying miRNA-mimicking siRNAs.
Saito, Takaya, Sætrom, Pål
openaire   +3 more sources

Multi-Dimensional Automatic Detection of Scanning Radar Images of Marine Targets Based on Radar PPInet

open access: yesRemote Sensing, 2021
Traditional radar target detection algorithms are mostly based on statistical theory. They have weak generalization capabilities for complex sea clutter environments and diverse target characteristics, and their detection performance would be ...
Xiaolong Chen   +5 more
doaj   +1 more source

Clinical proteomic analysis of scrub typhus infection

open access: yesClinical Proteomics, 2018
Background Scrub typhus is an acute and febrile infectious disease caused by the Gram-negative α-proteobacterium Orientia tsutsugamushi from the family Rickettsiaceae that is widely distributed in Northern, Southern and Eastern Asia. In the present study,
Edmond Changkyun Park   +9 more
doaj   +1 more source

From Video to Hyperspectral: Hyperspectral Image-Level Feature Extraction with Transfer Learning

open access: yesRemote Sensing, 2022
Hyperspectral image classification methods based on deep learning have led to remarkable achievements in recent years. However, these methods with outstanding performance are also accompanied by problems such as excessive dependence on the number of ...
Yifan Sun   +5 more
doaj   +1 more source

TLR9-mediated activation of dendritic cells by CD32 targeting for the generation of highly immunostimulatory vaccines

open access: yesHuman Vaccines & Immunotherapeutics, 2019
The rational for designing dendritic cell (DC)-targeted immunotherapies is their central role in orchestrating immunity. Most studies addressing antigen-targeting to DCs for eliciting T cell responses have employed ex-vivo matured DCs derived from ...
J. A. Sepulveda-Toepfer   +7 more
doaj   +1 more source

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