Results 61 to 70 of about 2,123,261 (297)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A Study on GHG Abatement Costs in Korea: International Emissions Trading and Major Sectors of Carbon Reduction

open access: yesEast Asian Economic Review, 2010
In this paper, we estimate the cost of the GHG abatement target by Korean government using a trade-based model, GTAP-E, after updating all the database of industrial and trade structures as well as carbon dioxide emissions of most of regions of the world.
Chang-Soo Lee , Nam-Yil Kim
doaj   +1 more source

Supply of renewable energy sources and the cost of EU climate policy [PDF]

open access: yes
What are the excess costs of a separate 20% target for renewable energy as a part of the EU climate policy for 2020? We answer this question using a computable general equilibrium model, WorldScan, which has been extended with a bottom-up module of the ...
J. Koornneef, Stefan Boeters
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

TUITION/PRICING FOR ONLINE LEARNING

open access: yesOnline Learning, 2019
To make online learning an integral part of higher education, institutions must determine the real costs of instruction and what tuition to charge based on these costs. Then the question is: Is this tuition bearable by the target population of potential
Karen Paulson
doaj   +1 more source

A modelling approach for allocating land-use in space to maximise social welfare - exemplified on the problem of wind power generation [PDF]

open access: yes
Land-use conflicts arise if land is scarce, land-use types are mutually exclusive, and vary in their effects with regard to more than one incongruent policy objective.
Drechsler, Martin   +4 more
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

MULTI-GAS EMISSION REDUCTION FOR CLIMATE CHANGE POLICY: AN APPLICATION OF FUND [PDF]

open access: yes
The costs of greenhouse gas emission reduction are investigated with abatement of carbon dioxide, methane, and nitrous oxide using the FUND model. The central policy scenario keeps anthropogenic radiative forcing below 4.5 Wm-2. If CO2 emission reduction
Richard S.J. Tol
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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