Results 91 to 100 of about 1,554,918 (266)

Targeted Therapies; Who Detects the Target?

open access: yesAnalytical Cellular Pathology, 2005
G. A. Meijer, J. J. Oudejans
openaire   +3 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Dim Range-Spread Target Detection for Stepped-Frequency Radar Using a Bernoulli Extended Target Filter

open access: yesSensors
Stepped-frequency radar is an important high range resolution radar. It can achieve wide overall bandwidth with narrow instant bandwidth. When the signal-to-noise ratio is low, detection and tracking become challenging due to dense false alarms and the ...
Fei Cai, Meiyu Tang
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Improved Multispectral Target Detection Using Target-Specific Spectral Reconstruction

open access: yesRemote Sensing
Hyperspectral sensors provide high spectral resolution, enabling accurate material discrimination and effective target detection. However, their practical use is constrained by limited spatial resolution and high acquisition costs.
Nicola Acito   +2 more
doaj   +1 more source

Target Driven Adaptive Loss for Infrared Small Target Detection

open access: yes2025 IEEE International Conference on Image Processing (ICIP)
We propose a target driven adaptive (TDA) loss to enhance the performance of infrared small target detection (IRSTD). Prior works have used loss functions, such as binary cross-entropy loss and IoU loss, to train segmentation models for IRSTD. Minimizing these loss functions guides models to extract pixel-level features or global image context. However,
Shoji, Yuho   +2 more
openaire   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Quantum Limits of Covert Target Detection

open access: yesPhysical Review Letters
20 pages, 5 ...
Guo Yao Tham, Ranjith Nair, Mile Gu
openaire   +4 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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