Results 81 to 90 of about 6,075,366 (305)
Interaction of HP1 and Brg1/Brm with the Globular Domain of Histone H3 Is Required for HP1-Mediated Repression [PDF]
, 2009 The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. These proteins contain two related domains known as the chromo- and the chromoshadow-domain.
Fan Hua-Ying +29 more
core +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Experiments on domain adaptation for English-Hindi SMT [PDF]
, 2009 Statistical Machine Translation (SMT) systems are usually trained on large amounts of bilingual text and monolingual target language text. If a significant amount of out-of-domain data is added to the training data, the quality of translation can drop ...
Way, Andy +3 more
core +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
On Target Shift in Adversarial Domain Adaptation
Proceedings of machine learning research, 2019 Discrepancy between training and testing domains is a fundamental problem in the generalization of machine learning techniques. Recently, several approaches have been proposed to learn domain invariant feature representations through adversarial deep learning. However, label shift, where the percentage of data in each class is different between domains,
Yitong Li 0001 +4 more
openaire +4 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Maritime Domain Protections Research Group (archived) [PDF]
, 2013 The Maritime Domain Protection Research Group (formerly known as the Maritime Domain Protection Task Force) was formed to investigate issues surrounding protection of the United States, its vessels, and citizens from terrorist threats originating in the ...
core +2 more sources
Domain-Invariant Partial-Least-Squares Regression
, 2018 Multivariate calibration models often fail to extrapolate beyond the calibration samples because of changes associated with the instrumental response, environmental condition, or sample matrix.
Ramin Nikzad-Langerodi (5211452) +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Domain Adaptation with Incomplete Target Domains [PDF]
, 2023 Domain adaptation, as a task of reducing the annotation cost in a target domain by exploiting the existing labeled data in an auxiliary source domain, has received a lot of attention in the research community.
Li, Zhenpeng +5 more
core +1 more source