Results 91 to 100 of about 6,075,366 (305)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Compiling a domain specific language for dynamic programming [PDF]
, 2006 Steffen P. Compiling a domain specific language for dynamic programming.
Steffen, Peter
core
The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae. [PDF]
, 2008 BACKGROUND: Streptococcus pneumoniae is the major cause of community-acquired pneumonia and is also associated with bronchitis, meningitis, otitis and sinusitis.
Laponogov, I +17 more
core +1 more source
Reiterative Domain Aware Multi-target Adaptation
, 2022 Most domain adaptation methods focus on single-source-single-target adaptation settings. Multi-target domain adaptation is a powerful extension in which a single classifier is learned for multiple unlabeled target domains. To build a multi-target classifier, it is important to have: a feature extractor that generalizes well across domains; and ...
Sudipan Saha +3 more
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Review of Embedding Methods and Domain Alignment Techniques in Dual-Target Cross-Domain Recommendation [PDF]
Jisuanji kexue yu tansuoAs a key branch of cross-domain recommendation technology, dual-target cross-domain recommendation improves the efficiency of source domain and target domain recommendation synchronously by virtue of a two-way collaborative optimization mechanism, and is
HU Siyu, MEI Hongyan, YANG Haiyan, CHENG Nai, ZHANG Xiaoyu
doaj +1 more source
Learning Transferable Convolutional Proxy by SMI-Based Matching Technique
Shock and Vibration, 2020 Domain-transfer learning is a machine learning task to explore a source domain data set to help the learning problem in a target domain. Usually, the source domain has sufficient labeled data, while the target domain does not. In this paper, we propose a
Wei Jin, Nan Jia
doaj +1 more source
Dense Retrieval Adaptation using Target Domain Description
, 2023 In information retrieval (IR), domain adaptation is the process of adapting a retrieval model to a new domain whose data distribution is different from the source domain.
Prasad, Srivas +5 more
core
The retinoblastoma protein modulates Tbx2 functional specificity [PDF]
, 2010 Tbx2 is a member of a large family of transcription factors defined by homology to the T-box DNA-binding domain. Tbx2 plays a key role in embryonic development, and in cancer through its capacity to suppress senescence and promote invasiveness.
Colin R. Goding +14 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source