Results 231 to 240 of about 321,270 (256)

An Engage or Retreat Differential Game with a Mobile Target

2021 IEEE Conference on Control Technology and Applications (CCTA), 2021
Swathi Chandrasekar, Zachariah E. Fuchs
openaire   +1 more source

Pharmacological Target Engagement and Validation

2022
openaire   +1 more source

Quantitative Kinase Target Engagement

Genetic Engineering & Biotechnology News, 2018
Kristin Huwiler, James Vasta, Cesear Corona, Chad Zimprich, Jennifer Wilkinson, Morgan Ingold, Matthew Robers   +6 more
openaire   +1 more source

Target Engagement and Pharmacotherapy in Eating Disorders

Abstract While eating disorders are severe psychiatric disorders, effective pharmacological therapies are largely lacking. To date, only two medications have been approved for the treatment of eating disorders: fluoxetine for bulimia nervosa and lisdexamfetamine for binge-eating disorder.
openaire   +1 more source

89Zr-Immuno-PET with Immune Checkpoint Inhibitors: Measuring Target Engagement in Healthy Organs

Cancers, 2023
Iris H C Miedema, Jessica E Wijngaarden, Johanna E E Pouw   +2 more
exaly  

Dose-Dependent Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia: A Double-Blind, Placebo-Controlled, Randomized, Target Engagement Clinical Trial of the NMDA Glutamate Receptor Agonist d-serine

Biological Psychiatry, 2023
Tse-Hwei Choo, Marlene Carlson, Joshua T Kantrowitz   +2 more
exaly  

Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery

SLAS Discovery, 2021
Dongyu Sun, Jongwon Lim, Jeremy Presland   +2 more
exaly  

High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms

SLAS Discovery, 2020
Brian A Sparling, Antony Symons
exaly  

A call for better understanding of target engagement in Tau antibody development

Drug Discovery Today, 2022
Anton Bespalov, Jean-Philippe Courade, Leonard Khiroug   +2 more
exaly  

The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies

Annual Review of Pharmacology and Toxicology, 2016
Daniel Martinez Molina, Par Nordlund
exaly