Results 221 to 230 of about 321,270 (256)
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Click Chemistry for Target Engagement Studies
The expanding number of targeted covalent small molecule inhibitors in clinical development increases the importance of identification and quantitation of on- and off-target engagement for these molecules in order to better understand the level of target binding and inhibition and potential side effects.Silvia, Castelli +2 more
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Dashboard, Target, and Engagement Tools
2020In the last chapter, we saw some basics about configuring the proxy, user options, and project options. In this chapter we’ll get started with getting familiar with the Burp Suite dashboard, target, and engagement tools.
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Threat-Aware Selection for Target Engagement
2022 IEEE 18th International Conference on Automation Science and Engineering (CASE), 2022Daniel Biediger, Aaron T. Becker
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Ground moving target engagement by cooperative UAVs
Proceedings of the 2005, American Control Conference, 2005., 2005The purpose of this tutorial paper is to present an application example for the MultiUAV cooperative control simulation. MultiUAV has been used to simulate a cooperative moving target engagement (CMTE) scenario, with a team of UAVs acting as a sensor and communication network to cooperatively track and attack moving ground targets.
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Study of Engagement with Mobile Targets
2012This study intends to describe a methodology and to provide the data required for a realistic analysis of a mobile target engagement. Specifically, it provides a means of estimating the probability that a target is still present at an observed location as a function of time from the observation where the time the target stopped is unknown.
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Improving the Accuracy of a Target Engagement Demonstration
Fusion Science and Technology, 2009In the High Average Power Laser (HAPL) program, we have developed an integrated target tracking and engagement system designed to track an inertial fusion energy target traveling 50-100 m/s in three dimensions and to steer laser driver beams so as to engage it with ± 20 μm accuracy from a standoff distance of ~20 meters. The system consists of separate
Lane Carlson +5 more
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Affordable moving surface target engagement
Proceedings, IEEE Aerospace Conference, 2003This paper presents the results of the Defense Advanced Research Project Agency-funded Affordable Moving Surface Target Engagement program. The overall objective was to develop affordable technologies to engage moving surface targets such as tanks, tactical ballistic missile transporters and small boats.
M. Veth +5 more
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Awake Testing to Confirm Target Engagement
2020Clinical testing of the awake patient during or prior to functional neurosurgical procedures such as deep brain stimulator (DBS) placement, focused ultrasound (FUS), or epilepsy surgeries is a valuable tool to verify that the appropriate target has been engaged for purposes of improving symptoms.
Neepa J. Patel +2 more
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Target Engagement with Transcranial Current Stimulation
2016Transcranial electric stimulation (tES) applies a weak electric current to the scalp, which causes an electric field that changes brain activity and behavior. Despite the rapidly growing number of studies that report successful modulation of behavior in both healthy participants and patients, little is known about how tES modulates brain activity.
Flavio Fröhlich +6 more
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Rapid Evaluation of Small Molecule Cellular Target Engagement with a Luminescent Thermal Shift Assay
ACS Medicinal Chemistry Letters, 2021Jonathan D Mortison +2 more
exaly