Results 41 to 50 of about 2,773,596 (266)
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom +15 more
wiley +1 more source
Functionalized nanosystems for targeted mitochondrial delivery [PDF]
Mitochondrial dysfunction including oxidative stress and DNA mutations underlies the pathology of various diseases including Alzheimer's disease and diabetes, necessitating the development of mitochondria targeted therapeutic agents. Nanotechnology offers unique tools and materials to target therapeutic agents to mitochondria.
Shelley A, Durazo, Uday B, Kompella
openaire +2 more sources
Functions and Targets of miR-335 in Cancer
MicroRNAs (miRNAs) are small non-coding RNAs (18~25 nt in length) that act as master regulators of eukaryotic gene expression. They might play an oncogenic or tumor-suppressive role in multiple cancers. In recent decades, several studies have focused on the functions and mechanisms of miR-335 in cancer.
Ye,Lingling +10 more
openaire +4 more sources
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
ECONOMIC SECURITY OF RUSSIA: A RENAISSANCE OF SYSTEMS APPROACH
The article describes the wave-like interest in the problem of ensuring Russia’s economic security, and points to the presence in the country of a strong political, business and criminal lobby that is not interested in the civilized legal development of ...
A. I. Selivanov
doaj +1 more source
Glioblastoma is the most common and aggressive primary tumor in the central nervous system, accounting for 12%–15% of all brain tumors. 3-O-Acetyl-11-keto-β-boswellic acid (AKBA), one of the most active ingredients of gum resin from Boswellia carteri ...
Wan Li +6 more
doaj +1 more source
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
MANAGEMENT OF TECHNOLOGICAL PROCESSES OF OPERATION OF WATER SYSTEMS
The article considers general approaches to the management of operating modes of water-bearing horizons in optimal regimes. The task is to justify the objective function of the object and to construct a regulator.
Anatoly Valentinovich Maikov
doaj
The problem of light trapping engineering for semiconductor surfaces covered with randomly distributed spheroidal metallic nanoparticles has been considered.
V.Z. Lozovski
doaj +1 more source
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source

