Results 21 to 30 of about 22,090 (255)
New Therapeutic Targets for Intraocular Pressure Lowering
ISRN Ophthalmology, 2013 Primary open-angle glaucoma (POAG) is a leading cause of irreversible and preventable blindness and ocular hypertension is the strongest known risk factor. With current classes of drugs, management of the disease focuses on lowering intraocular pressure (IOP). Despite of their use to modify the course of the disease, none of the current medications for
Rocha-Sousa, A. +6 more
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Journal of Ophthalmology, 2021 Background: Until now, no direct relationship has been established between the target pressure and particular corneal thickness for measurements with different types of tonometers.
Dmitriev S. K. +3 more
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Endocannabinoid metabolism and transport as targets to regulate intraocular pressure
Experimental Eye Research, 2020 Cannabinoids are part of an endogenous signaling system found throughout the body, including the eye. Hepler and Frank showed in the early 1970s that plant cannabinoids can lower intraocular pressure (IOP), an effect since shown to occur via cannabinoid CB1 and GPR18 receptors. Endocannabinoids are synthesized and metabolized enzymatically.
Sally, Miller +8 more
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The Outcomes of Bleb Revision Surgery Techniques After Trabeculectomy
Türk Oftalmoloji Dergisi, 2012 Pur po se: To evaluate the techniques and the results of revision surgeries in order to manage bleb failure after trabeculectomy. Ma te ri al and Met hod: The records of 23 eyes who had undergone bleb revision surgery because of bleb failure after ...
Orhan Ayar +5 more
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Therapeutic Advances in Ophthalmology, 2020 Background: Glaucoma is most common irreversible cause of blindness in India. First line management of open-angle glaucoma is either beta blockers or prostaglandin analogs monotherapy.
Alok Dixit, Atul Ashish, Reena Sharma
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Target IOP as a measure of glaucoma surgery efficacy
Oftalʹmologiâ, 2015 There are numerous criteria of glaucoma surgery efficacy. Among them, IOP level is of special importance. The development of tolerant and target IOP concepts as well as IOP tolerability issue are reviewed below.
S. Yu. Petrov
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Glaucoma: target intraocular pressures and current treatments [PDF]
Prescriber, 2009 Abstract Our Drug review of glaucoma management describes the use of target intraocular pressures in directing treatment, and the medical, laser and surgical management options. This is followed by an analysis of prescription data and sources of further information.
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Türk Oftalmoloji Dergisi, 2012 Pur po se: To evaluate the effects of latanoprost/timolol maleate and dorzolamid/timolol maleate fixed combinations on-24 hours intraocular pressure in patients with open-angle glaucoma.
Berna Yüce +3 more
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From Bench to Bed: The Current Genome Editing Therapies for Glaucoma
Frontiers in Cell and Developmental Biology, 2022 Glaucoma is a group of optic neuropathies featured by degeneration of retinal ganglion cells and loss of their axons in the optic nerve. The only currently approved therapies focus on lowering intraocular pressure with medication and surgery.
Meihui He +11 more
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Bangabandhu Sheikh Mujib Medical University Journal, 2016 Background: Intraocular pressure (IOP) is one of the most important parameters in the diagnosis and treatment of glaucoma. Glaucoma has been established as the second leading cause of blindness.
Sayed Abdul Wadud +2 more
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