Results 31 to 40 of about 22,960 (241)

From Bench to Bed: The Current Genome Editing Therapies for Glaucoma

Frontiers in Cell and Developmental Biology, 2022
Glaucoma is a group of optic neuropathies featured by degeneration of retinal ganglion cells and loss of their axons in the optic nerve. The only currently approved therapies focus on lowering intraocular pressure with medication and surgery.
Meihui He, Meihui He, Meihui He, Rong Rong, Rong Rong, Rong Rong, Dan Ji, Dan Ji, Dan Ji, Xiaobo Xia, Xiaobo Xia, Xiaobo Xia   +11 more
doaj   +1 more source

Surgery for normal tension glaucoma. Target intraocular pressure and visual field progression [PDF]

Acta Ophthalmologica Scandinavica, 1997
No abstract ...
Fontana L, Viswanathan AC, Poinooswamy D, Hitchings RA, Scullica L   +4 more
openaire   +3 more sources

Comparative study of intraocular pressure (IP) in Bangladeshi individuals by contact and non contact technique

Bangabandhu Sheikh Mujib Medical University Journal, 2016
Background: Intraocular pressure (IOP) is one of the most important parameters in the diagnosis and treatment of glaucoma. Glaucoma has been established as the second leading cause of blindness.
Sayed Abdul Wadud, Md. Sharfuddin Ahmad, Muntasir Bin Shahid   +2 more
doaj   +1 more source

Target Intraocular Pressure and Personalized Medicine in Glaucoma: Balancing Precision, Patient Autonomy, and Evolving Treatment Paradigms

TNOA Journal of Ophthalmic Science and Research
The establishment of a target intraocular pressure (IOP) remains the cornerstone of therapeutic intervention in glaucoma. However, the paradigm for defining this target has shifted dramatically from a population-based threshold to a fluid, individualized
Shibal Bhartiya, Prasanna Venkatesh Ramesh   +1 more
doaj   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Glaucoma: target intraocular pressures and current treatments [PDF]

Prescriber, 2009
Abstract Our Drug review of glaucoma management describes the use of target intraocular pressures in directing treatment, and the medical, laser and surgical management options. This is followed by an analysis of prescription data and sources of further information.
openaire   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Combined Femtosecond Laser Assisted Cataract Surgery and Pars Plana Vitrectomy

The Pan-American Journal of Ophthalmology, 2017
Purpose: Determine the benefits and challenges of combined femtosecond laser assisted cataract surgery with the Catalys® system (Abbott, Abbott Park, IL) and vitrectomy.
Brian Lee, Paul Drayna, Sandra R Montezuma   +2 more
doaj   +3 more sources

Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX

Biological and Pharmaceutical Bulletin, 2019
Elevated intraocular pressure (IOP) is the major cause of glaucoma, which is the second leading cause of blindness. However, current glaucoma treatments cannot completely regulate IOP and progression of glaucoma. Our group recently found that autotaxin (ATX) activity in human aqueous humor (AH) was positively correlated with increased IOP in various ...
Nagano, Norimichi, Honjo, Megumi, Kawaguchi, Mitsuyasu, Nishimasu, Hiroshi, Nureki, Osamu, Kano, Kuniyuki, Aoki, Junken, Komatsu, Toru, Okabe, Takayoshi, Kojima, Hirotatsu, Nagano, Tetsuo, Aihara, Makoto   +11 more
openaire   +3 more sources

Elevation of intraocular pressure in rodents using viral vectors targeting the trabecular meshwork [PDF]

Experimental Eye Research, 2015
Rodents are increasingly being used as glaucoma models to study ocular hypertension, optic neuropathy, and retinopathy. A number of different techniques are used to elevate intraocular pressure in rodent eyes by artificially obstructing the aqueous outflow pathway.
Iok-Hou, Pang, J Cameron, Millar, Abbot F, Clark   +2 more
openaire   +2 more sources