Results 41 to 50 of about 5,073,864 (289)

Comparative study of intraocular pressure (IP) in Bangladeshi individuals by contact and non contact technique

Bangabandhu Sheikh Mujib Medical University Journal, 2016
Background: Intraocular pressure (IOP) is one of the most important parameters in the diagnosis and treatment of glaucoma. Glaucoma has been established as the second leading cause of blindness.
Sayed Abdul Wadud, Md. Sharfuddin Ahmad, Muntasir Bin Shahid   +2 more
doaj   +1 more source

Target Intraocular Pressure and Personalized Medicine in Glaucoma: Balancing Precision, Patient Autonomy, and Evolving Treatment Paradigms

TNOA Journal of Ophthalmic Science and Research
The establishment of a target intraocular pressure (IOP) remains the cornerstone of therapeutic intervention in glaucoma. However, the paradigm for defining this target has shifted dramatically from a population-based threshold to a fluid, individualized
Shibal Bhartiya, Prasanna Venkatesh Ramesh   +1 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Glaucoma: target intraocular pressures and current treatments [PDF]

Prescriber, 2009
Abstract Our Drug review of glaucoma management describes the use of target intraocular pressures in directing treatment, and the medical, laser and surgical management options. This is followed by an analysis of prescription data and sources of further information.
openaire   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Combined Femtosecond Laser Assisted Cataract Surgery and Pars Plana Vitrectomy

The Pan-American Journal of Ophthalmology, 2017
Purpose: Determine the benefits and challenges of combined femtosecond laser assisted cataract surgery with the Catalys® system (Abbott, Abbott Park, IL) and vitrectomy.
Brian Lee, Paul Drayna, Sandra R Montezuma   +2 more
doaj   +3 more sources

Elevation of intraocular pressure in rodents using viral vectors targeting the trabecular meshwork [PDF]

Experimental Eye Research, 2015
Rodents are increasingly being used as glaucoma models to study ocular hypertension, optic neuropathy, and retinopathy. A number of different techniques are used to elevate intraocular pressure in rodent eyes by artificially obstructing the aqueous outflow pathway.
Iok-Hou, Pang, J Cameron, Millar, Abbot F, Clark   +2 more
openaire   +2 more sources

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Magnetic Resonance Conditional Microinjector

Journal of Imaging, 2018
Glaucoma, one of the leading causes of blindness, has been linked to increases in intraocular pressure. In order to observe and study this effect, proposed is a specialized microinjector and driver that can be used to inject small amounts of liquid into ...
Adam Wineland, Yue Chen, Brian Boland, Kevin Chan, Zion Tse   +4 more
doaj   +1 more source

Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX

Biological and Pharmaceutical Bulletin, 2019
Elevated intraocular pressure (IOP) is the major cause of glaucoma, which is the second leading cause of blindness. However, current glaucoma treatments cannot completely regulate IOP and progression of glaucoma. Our group recently found that autotaxin (ATX) activity in human aqueous humor (AH) was positively correlated with increased IOP in various ...
Nagano, Norimichi, Honjo, Megumi, Kawaguchi, Mitsuyasu, Nishimasu, Hiroshi, Nureki, Osamu, Kano, Kuniyuki, Aoki, Junken, Komatsu, Toru, Okabe, Takayoshi, Kojima, Hirotatsu, Nagano, Tetsuo, Aihara, Makoto   +11 more
openaire   +3 more sources