Results 141 to 150 of about 6,718,347 (301)

Rapport de M. Target sur un projet d'organisation du corps législatif, lors de la séance du 29 septembre 1789

open access: yes, 1877
Target Guy-Jean-baptiste. Rapport de M. Target sur un projet d'organisation du corps législatif, lors de la séance du 29 septembre 1789. In: Archives Parlementaires de 1787 à 1860 - Première série (1787-1799) Tome IX - Du 16 septembre au 11 novembre 1789.
Target, Guy Jean-Baptiste
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Supporting our sustainable future: a shared decision-guiding principle. [PDF]

open access: yesNatl Sci Rev
Zhang J   +24 more
europepmc   +1 more source

Consumer empowerment strategies: A rights oriented approach versus a needs-oriented approach

open access: yes, 2011
In this article we argue that a rights oriented approach alone cannot achieve effective consumer empowerment. A critical point that is often overlooked in the Commission’s striving to create and to fine-tune consumer rights, is that these rights do not ...
Mak, V.; id_orcid   +2 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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