Results 61 to 70 of about 569,729 (301)

Ambulatory arterial stiffness indices and target organ damage in hypertension

BMC Cardiovascular Disorders, 2012
Background The present study was designed to evaluate which arterial stiffness parameter - AASI or the home arterial stiffness index (HASI) - correlates best with vascular, cardiac and renal damage in hypertensive individuals.
Gómez-Marcos Manuel, Recio-Rodríguez José, Patino-Alonso Ma, Gómez-Sánchez Leticia, Agudo-Conde Cristina, Gómez-Sánchez Marta, Rodríguez-Sánchez Emiliano, García-Ortiz Luís   +7 more
doaj   +1 more source

Should Target Organ Damage Become a Therapeutic Target?

The Journal of Clinical Hypertension, 2013
In this issue of the Journal, Shlomai, Grassi, Grossman,and Mancia address the always “hot topic” of targetorgan damage in patients with hypertension in an articleentitled “Assessment of Target Organ Damage in theEvaluation and Follow-Up of the Hypertensive Patients:Where Do We Stand?” The article is thoughtful andinformative, considers the facts and ...
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics [PDF]

, 2019
Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR ...
Beattie, Bradley J., Beattie, Kai A., Elgqvist, Jörgen, Eriksson, Sophie E., Larsson, Erik, Strand, Sven-Erik, Thorek, Daniel L. J., Timmermand, Oskar Vilhelmsson, Tran, Thuy A., Ulmert, David, Örbom, Anders   +10 more
core   +2 more sources

Target organ damage in stress-induced arterial hypertension

Кардиоваскулярная терапия и профилактика, 2009
Aim. То investigate the features of target organ damage in patients with stress-induced arterial hypertension (AH).Material and methods. The study included 329 men, aged 29—55 years, with Stage I-II AH. Group I consisted of 197 individuals with workplace
O. N. Antropova, I. V. Osipova, N. А. Lobanova, K. I. Shakhmatova   +3 more
doaj  

P55 TARGET ORGAN DAMAGE AND BLOOD PRESSURE VARIABILITY IN HYPERTENSION

Artery Research, 2017
Purpose/Background/Objectives: Hypertension is associated with several markers of subclinical target organ damage (TOD). Short-term blood pressure variability (SBPV) is a prognostic factor for cardiovascular events in hypertensives.
Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Athanasios Angelis, Nikolaos Loakeimidis, Panagiotis Xaplanteris, Christos Georgakopoulos, Evangelia Sigala, Losif Koutagiar, Angeliki Rigatou, Dimitrios Tousoulis   +9 more
doaj   +1 more source

Sense of coherence and hypertensive target organ damage

Psychiatria Polska, 2019
Cel pracyNadciśnienie tętnicze może być powikłane uszkodzeniami narządowymi (oznaczanymi w języku angielskim skrótem TOD – target organ damage). Do chwili obecnej udało się zidentyfikować wiele różnych czynników powiązanych z rozwojem TOD. Jednak, zgodnie z naszą wiedzą, nie próbowano wyodrębnić zmiennych psychologicznych, które różnicują pacjentów z ...
Lech, Popiołek, Iwona, Gawlik, Olga, Siga, Anna, Dzieża-Grudnik, Małgorzata, Moląg, Paweł, Rodziński, Tomasz, Grodzicki, Jolanta, Walczewska, Krzysztof, Rutkowski   +8 more
openaire   +2 more sources

Target organ damage in black hypertensives. [PDF]

Circulation, 1977
A representative sample of black hypertensives has been appraised to determine candidacy for hypertension treatment. A total of 1759 black residents were successfully screened at home. Forty-one percent of the males and 33% of the females had diastolic blood pressures of 95 mm Hg or greater.
G, Entwisle, A Y, Apostolides, J R, Hebel, M M, Henderson   +3 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Downregulated serum 14, 15-epoxyeicosatrienoic acid is associated with abdominal aortic calcification in patients with primary aldosteronism [PDF]

, 2018
Patients with primary aldosteronism (PA) have increased risk of target-organ damage, among which vascular calcification is an important indicator of cardiovascular mortality.
Gao, Jingwei, He, Wanbing, Huang, Hui, Lin, Ying, Liu, Pinming, Shi, Guangzi, Touyz, Rhian M., Yan, Li, Zhang, Shaoling   +8 more
core   +1 more source