Results 61 to 70 of about 5,291,171 (287)
Aortic stiffness, pressure and flow pulsatility, and target organ damage.
Journal of applied physiology, 2018 Measures of aortic stiffness and pressure and flow pulsatility have emerged as correlates of and potential contributors to cardiovascular disease, dementia, and kidney disease.
G. Mitchell
semanticscholar +1 more source
, 2022 Primary nonalcoholic fatty liver disease (NAFLD) is bi-directionally associated with the metabolic syndrome and its constitutive features (“factors”: impaired glucose disposal, visceral obesity, arterial hypertension, and dyslipidemia).
Singal, Ashwani K. +3 more
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Target organ damage in stress-induced arterial hypertension
Кардиоваскулярная терапия и профилактика, 2009 Aim. То investigate the features of target organ damage in patients with stress-induced arterial hypertension (AH).Material and methods. The study included 329 men, aged 29—55 years, with Stage I-II AH. Group I consisted of 197 individuals with workplace
O. N. Antropova +3 more
doaj
P55 TARGET ORGAN DAMAGE AND BLOOD PRESSURE VARIABILITY IN HYPERTENSION
Artery Research, 2017 Purpose/Background/Objectives: Hypertension is associated with several markers of subclinical target organ damage (TOD). Short-term blood pressure variability (SBPV) is a prognostic factor for cardiovascular events in hypertensives.
Dimitrios Terentes-Printzios +9 more
doaj +1 more source
Diagnosis and management of resistant hypertension: state of the art
, 2018 Resistant hypertension is defined as a lack of ambulatory blood pressure response to optimized medical treatment after exclusion of secondary hypertension in patients who are fully adherent to antihypertensive therapy.
Staessen, Jan A. +11 more
core +1 more source
Excess aldosterone as a mechanism of resistant salt-sensitive arterial hypertension [PDF]
, 2022 Albeit vastly underdiagnosed, primary aldosteronism is the most common cause of arterial hypertension and particularly of drug-resistant arterial hypertension, a high-risk condition with a poor prognosis. A timely diagnosis followed by targeted treatment
Torresan, Francesca
core +5 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Relaxin does not improve Angiotensin II-induced target-organ damage.
PLoS ONE, 2014 Relaxin is a corpus-luteum produced protein hormone with vasodilatatory, anti-fibrotic, and angiogenic properties that are opposite to angiotensin (Ang) II. We investigated whether or not relaxin ameliorates Ang II-induced target-organ damage.
Nadine Haase +5 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source