Results 111 to 120 of about 2,083,638 (324)

Knockdown Resistance to DDT and Pyrethroids in the House Fly (Diptera: Muscidae): From Genetic Trait to Molecular Mechanism [PDF]

, 2017
Knockdown resistance to DDT and pyrethrins was the 1st insecticide resistance trait involving reduced target site sensitivity to be identified and isolated genetically.
Knipple, Douglas C., Soderlund, David M.
core  

Designing multifunctional chemical sensors using Ni and Cu doped carbon nanotubes [PDF]

, 2010
We demonstrate a "bottom up" approach to the computational design of a multifunctional chemical sensor. General techniques are employed for describing the adsorption coverage and resistance properties of the sensor based on density functional theory (DFT)
Arnold, Ayala, Brahim, Chalier, Chan, Collins, De Blauwe, Fagan, Fagan, Fürst, Garca-Lastra, García-Lastra, Hierold, Jensen, Klie, Kong, Kramberger, Krasheninnikov, Lassagne, Li, Lide, Morgan, Mortensen, Mowbray, Perdew, Rocha, Soler, Strange, Suenaga, Tu, Villalpando-Páez, Vo, Yagi, Yang, Yeung, Zheng, Zheng   +36 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage [PDF]

, 2008
Clerocidin (CL), a microbial diterpenoid, reacts with DNA via its epoxide group and stimulates DNA cleavage by type II DNA topoisomerases. The molecular basis of CL action is poorly understood.
Binaschi, Borgnetto, Brown, Cambau, Champoux, Corbett, Corbett, Ferrero, Fisher, Gatto, Higgins, Kawada, L. M. Fisher, M. Dias, M. Palumbo, Marians, Maxam, McCullough, Mizuuchi, Morrison, Pan, Pan, Pan, Pan, Pan, Peden, Pozzi, Richter, Richter, Richter, Shea, X. S. Pan, Yague, Yoshida, Zechiedrich   +34 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Multiple target site resistance to glyphosate in junglerice (Echinochloa colona) lines from California orchards.

Pest Management Science, 2018
BACKGROUND In California specialty cropping systems such as vineyards and orchards, Echinochloa colona is present as a summer annual weed. It is able to germinate throughout the growing season whenever favorable conditions are present, and management ...
Sarah Morran, Marcelo L. Moretti, C. Brunharo, A. Fischer, B. Hanson   +4 more
semanticscholar   +1 more source

Confirmation and Characterization of the First Case of Acetolactate Synthase (ALS)-Inhibitor—Resistant Wild Buckwheat (Polygonum convolvulus L.) in the United States

Agronomy, 2020
Wild buckwheat (Polygonum convolvulus L.) is a problem weed and ALS-inhibitors (e.g., chlorsulfuron) are commonly used for its management. Recently, a population of wild buckwheat (KSW-R) uncontrolled with ALS-inhibitors was found in a wheat field in ...
Balaji Aravindhan Pandian, Abigail Friesen, Martin Laforest, Dallas E. Peterson, P. V. Vara Prasad, Mithila Jugulam   +5 more
doaj   +1 more source

Detection of accase target-site resistant Alopecurus myosuroides huds (black-grass) in Belgian populations [PDF]

, 2009
Black-grass is a common grass weed, widely spread in Northern Europe and also in Belgium. For ages, it has been an increasing problem in industrial crops, especially winter cereals.
Bodson, Bernard, Henriet, François, Maréchal, Pierre-Yves   +2 more
core  

Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I [PDF]

, 2012
Background: Chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphatic leukemia (Ph + ALL) are caused by the t(9;22), which fuses BCR to ABL resulting in deregulated ABL-tyrosine kinase activity.
Badura, Susanne, Khateb, Mamduh, Mahajna, Jamal, Metodieva, Anna, Mian, Afsar Ali, Najajreh, Yousef, Ottmann, Oliver Gerhard, Ruimi, Nili, Ruthardt, Martin   +8 more
core   +1 more source

Target Site Insensitivity Detection in Deltamethrin Resistant Culex pipiens Complex in Iran

Iranian Journal of Public Health, 2020
Background: Some mosquito species which belong to the Culex. pipiens complex are primary vectors for West Nile virus, Sindbis, Dirofilaria immitis, and many arboviruses. Knockdown resistance (kdr) mutations in the voltage-gated sodium channel (VGSC) gene of Cx.
Reza ZEIDABADINEZHAD, Hassan VATANDOOST, Mohammad Reza ABAI, Navid DINPARAST DJADID, Abbasali RAZ, Mohammad Mahdi SEDAGHAT, Mohamad Ali OSHAGHI, Ahmad RAEISI, Neda ADIBI   +8 more
openaire   +3 more sources