Results 241 to 250 of about 4,789,466 (273)

Effectiveness of PCSK9 inhibitors: A Target Trial Emulation framework based on Real-World Electronic Health Records

open access: yesPLoS ONE
Giulia Barbati   +5 more
doaj  

Target Trial Emulation: Teaching Epidemiology and Beyond [PDF]

open access: yesEuropean Journal of Epidemiology, 2017
textabstractObservational epidemiology is continually held to thestandard of randomized trials. A typical epidemiology article references previous trials in the introduction (or reasons why trials are not feasible) and, when possible, compares the results to previous trials in the discussion. When the results
Jeremy A Labrecque, Sonja A Swanson
exaly   +6 more sources

“Target Trial Emulation” for Observational Studies — Potential and Pitfalls

open access: yesNew England Journal of Medicine
To improve the quality of observational studies, target trial emulation requires careful specification of design elements, analytic methods for addressing confounding, and reporting of sensitivity analyses.
Constantine Gatsonis   +2 more
exaly   +4 more sources

Target Trial Emulation

JAMA, 2022
This Guide to Statistics and Methods describes the use of target trial emulation to design an observational study so it preserves the advantages of a randomized clinical trial, points out the limitations of the method, and provides an example of its use.
Miguel A, Hernán   +2 more
openaire   +2 more sources

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