Results 251 to 260 of about 4,789,466 (273)

Emulating a Target Trial Using Observational Data

JAMA Internal Medicine
This Guide to Statistics and Methods discusses target trial emulation, including why to use it, limitations of the method, and how to interpret target trial emulation findings.
Basma N, Dib, Sonja A, Swanson
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Review of tools to support Target Trial Emulation

Journal of Biomedical Informatics
Randomized Controlled Trials (RCTs) are the gold standard for clinical evidence, but ethical and practical constraints sometimes necessitate or warrant the use of observational data. The aim of this study is to identify informatics tools that support the design and conduct of Target Trial Emulations (TTEs), a framework for designing observational ...
Christina Van Hal, Elmer V. Bernstam, Todd R. Johnson   +2 more
openaire   +2 more sources

Target Trial Emulation for Evaluating Health Policy

Annals of Internal Medicine
Target trial emulation is an approach to designing rigorous nonexperimental studies by "emulating" key features of a clinical trial. Most commonly used outside of policy contexts, this approach is also valuable for policy evaluation as policies typically are not randomly assigned.
Nicholas J. Seewald, Emma E. McGinty, Elizabeth A. Stuart   +2 more
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Target trial emulation: a primer for clinical research

Current Opinion in Epidemiology and Public Health
Purpose of review This primer outlines what emulation failure looks like, the biases arising from such failures, and how they can be addressed, enabling clinicians to design and interpret observational studies with greater causal validity.
Asma Syed, Suhail A. Doi
openaire   +1 more source

Target Trial Emulation for Clarity of Causal Questions

BJOG: An International Journal of Obstetrics & Gynaecology
Linked article: This is a mini commentary on Fernandez Turienzo et al., pp. 958–973 in this issue. To view this article, visit https://doi.org/10.1111/1471‐0528.70101 .
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Target Trial Emulation: A Framework for Causal Inference From Observational Data

JAMA - Journal of the American Medical Association, 2022
David E Leaf, Miguel Hernan
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The Implementation of Target Trial Emulation for Causal Inference: A Scoping Review

Journal of Clinical Epidemiology, 2023
Yan Yuan, Sandy Campbell, Hanxiao Zuo
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Older Adult Participation in Cancer Clinical Trials: A Systematic Review of Barriers and Interventions

Ca-A Cancer Journal for Clinicians, 2021
William P Tew, Gretchen G Kimmick, William Dale   +2 more
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Target Trial Emulation and Bias Through Missing Eligibility Data: An Application to a Study of Palivizumab for the Prevention of Hospitalization Due to Infant Respiratory Illness

American Journal of Epidemiology, 2023
Daniel Tompsett, Bianca Lucia De Stavola, Pia Hardelid   +2 more
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An Overview of Precision Oncology Basket and Umbrella Trials for Clinicians

Ca-A Cancer Journal for Clinicians, 2020
Jay J H Park, Kristian Thorlund, Grace Hsu   +2 more
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