Results 81 to 90 of about 3,752,482 (246)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
MedCommMessenger RNA (mRNA) vaccines have revolutionized infectious disease prevention and cancer immunotherapy due to their rapid development, potent immunogenicity, and flexible design.
Xiaochi Li +7 more
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Les systèmes de retraite dans l’Union Européenne
Espace populations sociétés, 2013 In the European Union, life expectancy is increasing, fertility is declining and baby-boomers are retiring. The rapid ageing of the population has a strong impact on social protection and public finances.
Marlène Lamy
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Application of the Linear-Quadratic model to targeted radionuclide therapy [PDF]
, 2011 PhDThe principal aim of this work was to test the hypothesis that the Linear-Quadratic (LQ) model of cell survival, developed for external beam radiotherapy (EBRT), could be extended to targeted radionuclide therapy (TRT) in order to predict dose ...
Murray, Iain
core +2 more sources
Targeted Therapy in Systemic Sclerosis
Rambam Maimonides Medical Journal, 2016 Targeted therapies use an understanding of the pathophysiology of a disease in an individual patient. Although targeted therapy for systemic sclerosis (SSc, scleroderma) has not yet reached the level of patient-specific treatments, recent developments in
Murray Baron
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Targeted delivery of boronic acids through bioconjugation
, 2022 In oncology, a predicament becomes apparent when considering the shared nature of a tumor and healthy tissue. Traditional chemotherapy employs potent cytotoxic small molecules with reasonable selectivity for rapidly-dividing cells.
Lopes, Ricardo M. R. M.
core
A Positive Analysis of Targeted Employment Protection Legislation [PDF]
, 2007 In many countries, Employment Protection Legislation (EPL) establishes less strict dismissal procedures for specific groups of workers. This paper builds a simple matching model with heterogeneous workers in order to analyze this feature of EPL.
Jimeno, Juan F. +5 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Drug Design, Development and Therapy, 2019 Vo Van Giau, Seong Soo A An, John Hulme Department of Bionano Technology, Gachon Bionano Research Institute, Gachon University, Seongnam-si, Gyeonggi-do, South Korea Abstract: The worldwide misuse of antibiotics and the subsequent rise of multidrug ...
Giau VV, An SSA, Hulme J
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