Results 61 to 70 of about 3,752,482 (246)

Targeted therapy and Immunotherapy in Advanced Endometrial cancer

, 2022
Endometrial cancer is the most common gynaecological cancer in western countries. The prevalence of EC is increasing at a rate of 1–2% every year. Advanced endometrial cancer has a 5-year survival rate of 59.6 percent for stage III disease and 28.6 ...
Algazzar, Mohab Hesham Youssef Ebrahim
core  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Targeted Hybrid Nanocarriers as Co-Delivery Systems for Enhanced Cancer Therapy [PDF]

Advanced Pharmaceutical Bulletin
Hybrid nanocarriers have realized a growing interest in drug delivery research because of the potential of being able to treat, manage or cure diseases that previously had limited therapy or cure.
Joan Onyebuchi Erebor, Elizabeth Oladoyin Agboluaje, Ava M. Perkins, Megha Krishnakumar, Ndidi Ngwuluka   +4 more
doaj   +1 more source

Targeted Therapy of Sarcoma

Sarcomas represent a heterogeneous group of tumors that are composed of a wide range of tumor types with different natural histories and therapeutic approaches. Recent discoveries have identified specific molecular alterations in the pathogenesis of many
Trent, Jonathan C, Ludwig, Joseph
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The Elephant in the Lab (and Field): Contamination in Aquatic Environmental DNA Studies

Frontiers in Ecology and Evolution, 2020
The rapid evolution of environmental (e)DNA methods has resulted in knowledge gaps in smaller, yet critical details like proper use of negative controls to detect contamination.
Adam J. Sepulveda, Patrick R. Hutchins, Meghan Forstchen, Madeline N. Mckeefry, Anna M. Swigris   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Targeted metabolomics to quantitatively profile changes in amino acids and phenolics at every step of amahewu production from two Zea Mays L. maize types (white and yellow)

Frontiers in Nutrition
Most existing research on amahewu has primarily examined the microbial and physicochemical properties of beverages, leaving the overall metabolite profile insufficiently characterized.
Sebotse Dolly Kgoale, Abdullahi Adekilekun Jimoh, Fidele Tugizimana, Fidele Tugizimana, Adrian Abrahams, Oluwafemi Ayodeji Adebo   +5 more
doaj   +1 more source

Targeted observations with an airborne wind lidar [PDF]

, 2005
This study investigates the possibilities and limitations of airborne Doppler lidar for adaptive observations over the Atlantic Ocean. For the first time, a scanning 2-µm Doppler lidar was applied for targeted measurements during the Atlantic The ...
Busen, Reinhold, Reitebuch, Oliver, Rahm, Stephan, Dörnbrack, Andreas, Weissmann, Martin   +4 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source