Results 281 to 290 of about 7,670,364 (343)

Machine learning-based prediction of ICU admission and mortality in Crimean-Congo hemorrhagic fever by using wide-range targeted metabolomics. [PDF]

BMC Infect Dis
Cephe A, Büyüktuna SA, Koçhan N, Zararsız GE, Yerlitaş Sİ, Doğan K, Kablan D, Bağcı G, Özer S, Baysal C, Kıymaz YÇ, Doğan HO, Zararsız G.   +12 more
europepmc   +1 more source

Mixed-Culture Fermentation of Coffee Pulp Induces Metabolomic Changes and Enhances Multi-Target Bioactivity Relevant to Androgenetic Alopecia

Anurak Muangsanguan, Warintorn Ruksiriwanich, Niphawan Panti, Kasirawat Sawangrat, Pattarapa Pummara, Pornchai Rachtanapun, Korawan Sringarm, Sarana Rose Sommano, Sucheewin Krobthong, Chaiwat Arjin, Apinya Satsook, Juan Manuel Castagnini   +11 more
openalex   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Non-targeted metabolomics reveals metabolic signatures associated with <i>Clostridioides difficile</i> virulence. [PDF]

Front Microbiol
Pan H, Zhang M, Zhao D, Wang Q, Shang H, Luo Y.   +5 more
europepmc   +1 more source

Fecal metabolomic profiles by LDL-C target achievement status in statin-treated patients: a cross-sectional study

Yi‐Hsueh Liu, Wei‐Chun Hung, Ping-Hsun Wu, Po Peng, Pei-Yu Wu, Jiun‐Chi Huang, Yi‐Hsiung Lin, Szu‐Chia Chen   +7 more
openalex   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Widely Targeted Metabolomics Reveals Dynamic Secondary Metabolite Accumulation and Antioxidant Biomarkers Across Ripening Stages of <i>Ziziphus jujuba</i> cv. 'Junzao' Fruit. [PDF]

Antioxidants (Basel)
Yan Y, Zhang C, Tao Y, Feng Z.
europepmc   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

Widely Targeted Metabolomics Reveals Differences in Secondary Metabolites in Oats With Different Grain Hardness. [PDF]

Food Sci Nutr
Zhang D, Liu H, Guo Y, Chen G, Chen M, Xian X, Zhang Y, Han B.   +7 more
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source